7-oxo-1a-phenyl-7,7a-dihydro-1aH-oxireno[2,3-b]chromene-4,6-diyl diacetate

Base Information

• Chemical Name: 7-oxo-1a-phenyl-7,7a-dihydro-1aH-oxireno[2,3-b]chromene-4,6-diyl diacetate
• CAS No.: 1265223-32-2
• Molecular Formula: C₁₉H₁₄O₇
• Molecular Weight: 354.316
• Mol file: 1265223-32-2.mol

Synonyms:7-oxo-1a-phenyl-7,7a-dihydro-1aH-oxireno[2,3-b]chromene-4,6-diyl diacetate

Chemical Property of 7-oxo-1a-phenyl-7,7a-dihydro-1aH-oxireno[2,3-b]chromene-4,6-diyl diacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-oxo-1a-phenyl-7,7a-dihydro-1aH-oxireno[2,3-b]chromene-4,6-diyl diacetate

There total 2 articles about 7-oxo-1a-phenyl-7,7a-dihydro-1aH-oxireno[2,3-b]chromene-4,6-diyl diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

5,7-di-O-acetyl chrysin (6665-78-7) → 7-oxo-1a-phenyl-7,7a-dihydro-1aH-oxireno[2,3-b]chromene-4,6-diyl diacetate (1265223-32-2)

Guidance literature:

With 3,3-dimethyldioxirane; In dichloromethane; at 0 - 20 ℃; for 75h; Molecular sieve;

DOI:10.1016/j.tet.2010.11.076

Reference yield:

5,7-dihydroxy-2-phenyl-chromen-4-one (480-40-0) → 7-oxo-1a-phenyl-7,7a-dihydro-1aH-oxireno[2,3-b]chromene-4,6-diyl diacetate (1265223-32-2)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 60 h / 20 °C

2: 3,3-dimethyldioxirane / dichloromethane / 51 h / 0 - 20 °C / Molecular sieve

With pyridine; 3,3-dimethyldioxirane; In dichloromethane;

Reference yield: 88.0%

7-oxo-1a-phenyl-7,7a-dihydro-1aH-oxireno[2,3-b]chromene-4,6-diyl diacetate (1265223-32-2) → 3-hydroxy-4-oxo-2-phenyl-4H-chromene-5,7-diyl diacetate (1265223-39-9)

Guidance literature:

With toluene-4-sulfonic acid; In dichloromethane; at 20 ℃; for 18h;

DOI:10.1016/j.tet.2010.11.076

upstream raw materials:

5,7-di-O-acetyl chrysin

5,7-dihydroxy-2-phenyl-chromen-4-one

Downstream raw materials:

3-hydroxy-4-oxo-2-phenyl-4H-chromene-5,7-diyl diacetate