methyl 4-(3'-n-butyl-5',6',7',8'-tetrahydro-5',5',8',8'-tetramethyl-2'-naphthalenecarbonyl)benzoate

Base Information

• Chemical Name: methyl 4-(3'-n-butyl-5',6',7',8'-tetrahydro-5',5',8',8'-tetramethyl-2'-naphthalenecarbonyl)benzoate
• CAS No.: 758690-03-8
• Molecular Formula: C₂₇H₃₄O₃
• Molecular Weight: 406.565
• Mol file: 758690-03-8.mol

Synonyms:methyl 4-(3'-n-butyl-5',6',7',8'-tetrahydro-5',5',8',8'-tetramethyl-2'-naphthalenecarbonyl)benzoate

Chemical Property of methyl 4-(3'-n-butyl-5',6',7',8'-tetrahydro-5',5',8',8'-tetramethyl-2'-naphthalenecarbonyl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4-(3'-n-butyl-5',6',7',8'-tetrahydro-5',5',8',8'-tetramethyl-2'-naphthalenecarbonyl)benzoate

There total 3 articles about methyl 4-(3'-n-butyl-5',6',7',8'-tetrahydro-5',5',8',8'-tetramethyl-2'-naphthalenecarbonyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Monomethyl terephthalate (1679-64-7) → methyl 4-(3'-n-butyl-5',6',7',8'-tetrahydro-5',5',8',8'-tetramethyl-2'-naphthalenecarbonyl)benzoate (758690-03-8)

Guidance literature:

Multi-step reaction with 2 steps

1: (COCl)2 / benzene / 2 h / Heating

2: 820 mg / AlCl₃ / CH₂Cl₂ / 0.5 h / Heating

With aluminium trichloride; oxalyl dichloride; In dichloromethane; benzene; 2: Friedel-Crafts reaction;

DOI:10.1021/jm030651g

Reference yield:

6-bromo-1,2,3,4-tetrahydro-1,1,4,4-tetramethylnaphthalene (27452-17-1) → methyl 4-(3'-n-butyl-5',6',7',8'-tetrahydro-5',5',8',8'-tetramethyl-2'-naphthalenecarbonyl)benzoate (758690-03-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran; hexane / 1 h / 20 °C

1.2: 83 percent / tetrahydrofuran; hexane / 0.5 h / 20 °C

2.1: 820 mg / AlCl₃ / CH₂Cl₂ / 0.5 h / Heating

With n-butyllithium; aluminium trichloride; In tetrahydrofuran; hexane; dichloromethane; 2.1: Friedel-Crafts reaction;

DOI:10.1021/jm030651g

Reference yield:

4-Methoxycarbonylbenzoyl chloride (7377-26-6) + 6-n-butyl-1,2,3,4-tetrahydro-1,1,4,4-tetramethylnaphthalene (189698-30-4) → methyl 4-(3'-n-butyl-5',6',7',8'-tetrahydro-5',5',8',8'-tetramethyl-2'-naphthalenecarbonyl)benzoate (758690-03-8)

Guidance literature:

With aluminium trichloride; In dichloromethane; for 0.5h; Heating;

DOI:10.1021/jm030651g

upstream raw materials:

4-Methoxycarbonylbenzoyl chloride

6-n-butyl-1,2,3,4-tetrahydro-1,1,4,4-tetramethylnaphthalene

Monomethyl terephthalate

6-bromo-1,2,3,4-tetrahydro-1,1,4,4-tetramethylnaphthalene

Downstream raw materials:

4-[1-(3-butyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid methyl ester