27452-17-1

Basic information

• Product Name: 6-BROMO-1,1,4,4-TETRAMETHYL-1,2,3,4-TETRAHYDRONAPHTHALENE
• Synonyms: 6-BROMO-1,1,4,4-TETRAMETHYL-1,2,3,4-TETRAHYDRONAPHTHALENE;6-Bromo-1,1,4,4-tetramethyl-1,;6-Bromo-1,1,4,4-tetramethyltetralin;6-BROMO-1,1,4,4-TETRAMETHYL-1,2,3,4-TETRAHYDROPHTHALENE
• CAS NO: 27452-17-1
• Molecular Formula: C₁₄H₁₉Br
• Molecular Weight: 267.2
• Product Categories: Halides;Fused Ring Systems
• Mol File: 27452-17-1.mol
• Article Data: 23

Chemical Properties

• Melting Point: 34 °C
• Boiling Point: 110-115°C
• Flash Point: 126.631 °C
• Appearance: /
• Density: 1.165 g/cm³
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.517
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility: Insoluble in water
• CAS DataBase Reference: 6-BROMO-1,1,4,4-TETRAMETHYL-1,2,3,4-TETRAHYDRONAPHTHALENE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BROMO-1,1,4,4-TETRAMETHYL-1,2,3,4-TETRAHYDRONAPHTHALENE(27452-17-1)
• EPA Substance Registry System: 6-BROMO-1,1,4,4-TETRAMETHYL-1,2,3,4-TETRAHYDRONAPHTHALENE(27452-17-1)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 23-26-36/37/39
• Hazardous Substances Data: 27452-17-1(Hazardous Substances Data)

Usage

Uses

6-Bromo-1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthalene is used in Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation.

InChI:InChI=1/C14H19Br/c1-13(2)7-8-14(3,4)12-9-10(15)5-6-11(12)13/h5-6,9H,7-8H2,1-4H3

Upstream product

• 6683-46-1 1,1,4,4-Tetramethyl-1,2,3,4-tetrahydro-naphthalene 
• 6223-78-5 2,5-dichloro-2,5-dimethyl hexane 
• 92050-16-3 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylamine 
• 110-03-2 2,5-dimethyl-2,5-hexanediol 
• 108-86-1 bromobenzene 

Downstream Products

• 92654-79-0 5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphthalene-2-carboxaldehyde 
• 188844-71-5 5,5,8,8-tetramethyl-N-(2-nitrophenyl)-5,6,7,8-tetrahydronaphthalen-2-amine 
• 120081-57-4 N-ethyl 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl) hydroxy methyl] phenyl sulfonamide 
• 1027501-33-2 N-{5,5,8,8-Tetramethyl-3-[methyl-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amino]-5,6,7,8-tetrahydro-naphthalen-2-yl}-terephthalamic acid methyl ester 
• 1027488-38-5 4-(1,1,4,4,6,8,8,11,11-Nonamethyl-2,3,4,6,8,9,10,11-octahydro-1H-6,13-diaza-cyclohepta[1,2-b;4,5-b']dinaphthalen-14-yl)-benzoic acid methyl ester 
• 245369-52-2 Methyl 4-[1-(5,6,7,8-tetrahydro-3-trifluoromethyl-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoate 
• 1026393-85-0 4-(5-heptyl-7,7,10,10-tetramethyl-7,8,9,10-tetrahydro-5H-5,13-diaza-benzo[4,5]cyclohepta[1,2-b]naphthalen-12-yl)-benzoic acid methyl ester 
• 1027252-54-5 N-{2-[heptyl-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amino]-phenyl}-terephthalamic acid methyl ester 
• 1027510-29-7 4-(7,7,10,10-tetramethyl-5-pentyl-7,8,9,10-tetrahydro-5H-5,13-diaza-benzo[4,5]cyclohepta[1,2-b]naphthalen-12-yl)-benzoic acid methyl ester 
• 1026723-42-1 N-{5-methoxy-2-[propyl-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amino]-phenyl}-terephthalamic acid methyl ester 
• 1026646-43-4 N-{2-[pentyl-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amino]-phenyl}-terephthalamic acid methyl ester 

Relevant articles and documents

Phosphine-Catalyzed Difunctionalization of β-Fluoroalkyl α,β-Enones: A Direct Approach to β-Amino α-Diazo Carbonyl Compounds

An efficient and practical phosphine-catalyzed vicinal difunctionalization of β-fluoroalkyl α,β-enones with TMSN3 has been developed. Using dppb as the catalyst, the reaction worked efficiently to yield various β-amino α-diazocarbonyl compounds in high yields (up to 94 %). This work marks the first efficient construction of α-diazocarbonyl compounds by phosphine catalysis. Meanwhile, the asymmetric variant induced by the nucleophilic bifunctional phosphine P4 led to various chiral fluoroalkylated β-amino α-diazocarbonyl compounds in high yields and enantioselectivity. NMR and ESI-MS studies support the existence of the key reaction intermediates. In contrast, β-azide carbonyl compounds would be furnished in good yields from β-fluoroalkylated β,β-disubstituted enones.

aromatic compound having fused cyclic substituent in aromatic ring and organic light-emitting diode including the same

The present invention relates to a compound having a cyclic substituent fused with a cyclic ring and an organic light emitting diode including the same, and more particularly, to a compound for an organic light emitting diode represented by chemical formula A and an organic light emitting diode including the same. In chemical formula A, X is a substituent having structural formula X, Y is a substituent of structural formula Y1, n is an integer from 1 to 4, and structural formulas X and Y1 are the same as described in detailed description of the present invention.

COMPOUNDS AND METHODS FOR INHIBITING CYP26 ENZYMES

Compounds described herein are inhibitors of retinoic acid inducible P450 (CYP26) enzymes, and are useful for treating diseases that are responsive to retinoids. Certain compounds have retinoid activity, are resistant to CYP26-mediated catabolism, and are used for treating diseases that are responsive to retinoids.