2-methyl-benzoic acid 4-methyl-2-(2-methyl-benzoyl)-phenyl ester

Base Information

• Chemical Name: 2-methyl-benzoic acid 4-methyl-2-(2-methyl-benzoyl)-phenyl ester
• CAS No.: 794513-65-8
• Molecular Formula: C₂₃H₂₀O₃
• Molecular Weight: 344.41
• Mol file: 794513-65-8.mol

Synonyms:2-methyl-benzoic acid 4-methyl-2-(2-methyl-benzoyl)-phenyl ester

Chemical Property of 2-methyl-benzoic acid 4-methyl-2-(2-methyl-benzoyl)-phenyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-methyl-benzoic acid 4-methyl-2-(2-methyl-benzoyl)-phenyl ester

There total 2 articles about 2-methyl-benzoic acid 4-methyl-2-(2-methyl-benzoyl)-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

ortho-toluoyl chloride (933-88-0) + (2-Hydroxy-5-methyl-phenyl)-o-tolyl-methanone (147029-79-6) → 2-methyl-benzoic acid 4-methyl-2-(2-methyl-benzoyl)-phenyl ester (794513-65-8)

Guidance literature:

With sodium hydroxide;

DOI:10.1016/j.bmcl.2004.08.014

Reference yield:

p-tolyl 2-methylbenzoate (23597-25-3) → 2-methyl-benzoic acid 4-methyl-2-(2-methyl-benzoyl)-phenyl ester (794513-65-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / AlCl₃ / nitrobenzene / 0.75 h / 80 - 90 °C

2: 79 percent / NaOH / H₂O / 0.25 h

With sodium hydroxide; aluminium trichloride; In water; nitrobenzene; 1: Fries rearrangement;

DOI:10.1016/j.bmc.2007.02.051

Reference yield: 78.0%

2-methyl-benzoic acid 4-methyl-2-(2-methyl-benzoyl)-phenyl ester (794513-65-8) → [2-hydroxy-5-methyl-3-(2-methyl-benzoyl)-phenyl]-o-tolyl-methanone

Guidance literature:

With Montmorillonite K 10 clay; microwave irradiation;

DOI:10.1016/j.bmcl.2004.08.014

upstream raw materials:

ortho-toluoyl chloride

(2-Hydroxy-5-methyl-phenyl)-o-tolyl-methanone

p-tolyl 2-methylbenzoate