N-benzoyl-N'-methyl-N'-(4-chlorobenzenesulfonyl)hydrazine

Base Information

• Chemical Name: N-benzoyl-N'-methyl-N'-(4-chlorobenzenesulfonyl)hydrazine
• CAS No.: 1051380-22-3
• Molecular Formula: C₁₄H₁₃ClN₂O₃S
• Molecular Weight: 324.788
• Mol file: 1051380-22-3.mol

Synonyms:N-benzoyl-N'-methyl-N'-(4-chlorobenzenesulfonyl)hydrazine

Chemical Property of N-benzoyl-N'-methyl-N'-(4-chlorobenzenesulfonyl)hydrazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of N-benzoyl-N'-methyl-N'-(4-chlorobenzenesulfonyl)hydrazine

There total 5 articles about N-benzoyl-N'-methyl-N'-(4-chlorobenzenesulfonyl)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

benzoic acid-(N'-methyl-hydrazide); hydrochloride (1483-23-4) + 4-chlorobenzenesulfonyl chloride (98-60-2) → N-benzoyl-N'-methyl-N'-(4-chlorobenzenesulfonyl)hydrazine (1051380-22-3)

Guidance literature:

With dmap; triethylamine; In chloroform; at 20 ℃; for 24h;

DOI:10.2174/157017810791514670

Reference yield:

(phenyl-[1,3,4]oxadiazol-2-ylmercapto)-acetic acid amide → N-benzoyl-N'-methyl-N'-(4-chlorobenzenesulfonyl)hydrazine (1051380-22-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate; acetic acid / 1,4-dioxane / 10 °C / Reflux

2: dmap; triethylamine / chloroform / 24 h / 20 °C

With dmap; sodium tetrahydroborate; acetic acid; triethylamine; In 1,4-dioxane; chloroform;

DOI:10.2174/157017810791514670

Reference yield:

(phenyl-[1,3,4]oxadiazol-2-ylmercapto)-acetic acid ethyl ester (104496-93-7) → N-benzoyl-N'-methyl-N'-(4-chlorobenzenesulfonyl)hydrazine (1051380-22-3)

Guidance literature:

Multi-step reaction with 3 steps

1: ammonia / ethanol

2: sodium tetrahydroborate; acetic acid / 1,4-dioxane / 10 °C / Reflux

3: dmap; triethylamine / chloroform / 24 h / 20 °C

With dmap; sodium tetrahydroborate; ammonia; acetic acid; triethylamine; In 1,4-dioxane; ethanol; chloroform;

DOI:10.2174/157017810791514670

upstream raw materials:

(phenyl-[1,3,4]oxadiazol-2-ylmercapto)-acetic acid ethyl ester

benzoic acid-(N'-methyl-hydrazide); hydrochloride

4-chlorobenzenesulfonyl chloride

benzoic acid hydrazide