12-MERCAPTODODECANOIC ACID

Base Information

• Chemical Name: 12-MERCAPTODODECANOIC ACID
• CAS No.: 82001-53-4
• Molecular Formula: C12H24 O2 S
• Molecular Weight: 232.38
• Hs Code.: 2930909090
• Mol file: 82001-53-4.mol

Synonyms:12-Mercaptododecanoicacid

Chemical Property of 12-MERCAPTODODECANOIC ACID

Chemical Property:

• Vapor Pressure: 2.26E-06mmHg at 25°C
• Melting Point: 46-50 °C
• Refractive Index: 1.482
• Boiling Point: 366.5°C at 760 mmHg
• PKA: 4.78±0.10(Predicted)
• Flash Point: 175.4°C
• PSA: 76.10000
• Density: 0.987g/cm³
• LogP: 3.90180
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

12-Mercaptododecanoic acid 96% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 12-MERCAPTODODECANOIC ACID is used to produce hydrophilic SAMs. The resulting monolayers which are terminated with carboxylic acids can be further functionalized to introduce more complex end groups. Used in a study of the effect of molecular structure on the precision of copper-bound α,ω-mercaptoalkanoic acid "molecular ruler" stacks.

Technology Process of 12-MERCAPTODODECANOIC ACID

There total 7 articles about 12-MERCAPTODODECANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

12-((ethoxy(thiocarbonyl))thio)dodecanoic acid (60908-53-4) → 12-mercaptododecanoic acid (82001-53-4)

Guidance literature:

With sodium tetrahydroborate; In ethanol; ethylenediamine;

DOI:10.1016/S0040-4039(00)96114-8

Reference yield: 85.0%

12-acetylsulfanildodecanoic acid (352439-40-8) → 12-mercaptododecanoic acid (82001-53-4)

Guidance literature:

12-acetylsulfanildodecanoic acid; With sodium hydroxide; In methanol; at 20 ℃; for 3h;

With hydrogenchloride; In water;

DOI:10.1039/c3ob40659h

Reference yield: 83.0%

12-bromododecanoic acid (73367-80-3) → 12-mercaptododecanoic acid (82001-53-4)

Guidance literature:

12-bromododecanoic acid; With thiourea; In ethanol; for 24h; Reflux; Inert atmosphere;

With sodium hydroxide; for 6h; Inert atmosphere; Heating;

DOI:10.1016/j.ejmech.2017.10.062

upstream raw materials:

12-((ethoxy(thiocarbonyl))thio)dodecanoic acid

12-acetylsulfanildodecanoic acid

1,11-dodecadiene

1,12-dodecandiol

Downstream raw materials:

12-{(11-Carboxy-undecylsulfanyl)-[4-(3-trifluoromethyl-3H-diazirin-3-yl)-phenyl]-methylsulfanyl}-dodecanoic acid

12-[(11-Carboxy-undecylsulfanyl)-phenyl-methylsulfanyl]-dodecanoic acid

C₃₁H₄₇F₄N₃O₄S₂