(2R,4R)-2,5-Bis-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-pentanoic acid (2-allyl-phenyl)-amide

Base Information

• Chemical Name: (2R,4R)-2,5-Bis-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-pentanoic acid (2-allyl-phenyl)-amide
• CAS No.: 114877-80-4
• Molecular Formula: C₄₆H₅₅NO₄Si₂
• Molecular Weight: 742.118

Synonyms:(2R,4R)-2,5-Bis-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-pentanoic acid (2-allyl-phenyl)-amide

Chemical Property of (2R,4R)-2,5-Bis-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-pentanoic acid (2-allyl-phenyl)-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,4R)-2,5-Bis-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-pentanoic acid (2-allyl-phenyl)-amide

There total 2 articles about (2R,4R)-2,5-Bis-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-pentanoic acid (2-allyl-phenyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-allyl-phenylamine (32704-22-6) + (3S,5S)-3-(tert-Butyl-diphenyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-dihydro-furan-2-one (114877-77-9) → (2S,4S)-2,5-Bis-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-pentanoic acid (2-allyl-phenyl)-amide (114877-80-4)

Guidance literature:

With dimethylaluminum chloride;

DOI:10.1021/jo00275a015

Reference yield: 81.0%

2-allyl-phenylamine (32704-22-6) + (3R,5R)-3-(tert-Butyl-diphenyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-dihydro-furan-2-one (114877-77-9) → (2R,4R)-2,5-Bis-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-pentanoic acid (2-allyl-phenyl)-amide (114877-80-4)

Guidance literature:

With dimethylaluminum chloride; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4039(00)95503-5

Reference yield: 76.0%

tert-butyldimethylsilyl chloride (18162-48-6) + (2S,4S)-2,5-Bis-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-pentanoic acid (2-allyl-phenyl)-amide (114877-80-4) → (2S,4S)-4-(tert-Butyl-dimethyl-silanyloxy)-2,5-bis-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid (2-allyl-phenyl)-amide (114904-27-7)

Guidance literature:

DOI:10.1021/jo00275a015

upstream raw materials:

2-allyl-phenylamine

(3R,5R)-3-(tert-Butyl-diphenyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-dihydro-furan-2-one

(3S,5S)-3-(tert-Butyl-diphenyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-dihydro-furan-2-one

Downstream raw materials:

(2R,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-2,5-bis-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid (2-allyl-phenyl)-amide

(2S,4S)-4-(tert-Butyl-dimethyl-silanyloxy)-2,5-bis-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid

(2S,4S)-4-(tert-Butyl-dimethyl-silanyloxy)-2,5-bis-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid (2-allyl-phenyl)-amide

(2S,4S)-4-(tert-Butyl-dimethyl-silanyloxy)-2,5-bis-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 114877-80-4 (2R,4R)-2,5-Bis-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-pentanoic acid (2-allyl-phenyl)-amide

Send

Send

Metric Ton KG G Pound L ML

Send

Send