Benzyl 5-oxo-2-(phenylmethoxycarbonylamino)oxolane-2-carboxylate

Base Information

Chemical Name:Benzyl 5-oxo-2-(phenylmethoxycarbonylamino)oxolane-2-carboxylate
CAS No.:104754-52-1
Molecular Formula:C₂₀H₁₉NO₆
Molecular Weight:369.374
Hs Code.:
DSSTox Substance ID:DTXSID701130348

Synonyms:104754-52-1;benzyl 5-oxo-2-(phenylmethoxycarbonylamino)oxolane-2-carboxylate;benzyl 2-{[(benzyloxy)carbonyl]amino}-5-oxooxolane-2-carboxylate;benzyl 2-(((benzyloxy)carbonyl)amino)-5-oxotetrahydrofuran-2-carboxylate;ChemDiv3_000047;Oprea1_544933;DTXSID701130348;HMS1473C03;AKOS003622310;IDI1_019365;NCGC00174511-01;SR-01000388320;SR-01000388320-1;Z57107756;F0797-0086;Phenylmethyl tetrahydro-5-oxo-2-[[(phenylmethoxy)carbonyl]amino]-2-furancarboxylate

Suppliers and Price of Benzyl 5-oxo-2-(phenylmethoxycarbonylamino)oxolane-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzyl 5-oxo-2-(phenylmethoxycarbonylamino)oxolane-2-carboxylate

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:369.12123733
Heavy Atom Count:27
Complexity:539

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(OC1=O)(C(=O)OCC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3

Technology Process of Benzyl 5-oxo-2-(phenylmethoxycarbonylamino)oxolane-2-carboxylate

There total 3 articles about Benzyl 5-oxo-2-(phenylmethoxycarbonylamino)oxolane-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 104754-51-0
N-benzyloxycarbonyl-2-aminotetrahydro-5-oxo-2-furancarboxylic acid

: 100-39-0
benzyl bromide

: 104754-52-1
benzyl N-benzyloxycarbonyl-2-aminotetrahydro-5-oxo-2-furancarboxylate

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 90 ℃; for 2h;
DOI:10.1016/S0040-4020(01)96774-2

Reference yield:

: 328-50-7
α-ketoglutaric acid

: 104754-52-1
benzyl N-benzyloxycarbonyl-2-aminotetrahydro-5-oxo-2-furancarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / 4 h / 80 °C / 10 - 15 Torr

2: 84 percent / Et₃N / dimethylformamide / 2 h / 90 °C

With triethylamine; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)96774-2

Reference yield:

: 621-84-1
O-benzyl carbamate

: 104754-52-1
benzyl N-benzyloxycarbonyl-2-aminotetrahydro-5-oxo-2-furancarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / 4 h / 80 °C / 10 - 15 Torr

2: 84 percent / Et₃N / dimethylformamide / 2 h / 90 °C

With triethylamine; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)96774-2