1-ACETOXY-4-CHLORO-2-METHOXYBENZENE

Base Information

• Chemical Name: 1-ACETOXY-4-CHLORO-2-METHOXYBENZENE
• CAS No.: 85430-09-7
• Molecular Formula: C₉H₉ClO₃
• Molecular Weight: 200.622
• Hs Code.: 2915390090
• Mol file: 85430-09-7.mol

Synonyms:Phenol,4-chloro-2-methoxy-, acetate (9CI)

Chemical Property of 1-ACETOXY-4-CHLORO-2-METHOXYBENZENE

Chemical Property:

• PSA: 35.53000
• LogP: 2.27390
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-2-methoxyphenylacetate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-ACETOXY-4-CHLORO-2-METHOXYBENZENE

There total 1 articles about 1-ACETOXY-4-CHLORO-2-METHOXYBENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methoxyphenyl acetate (613-70-7) + 2-acetoxy-4-chloro-1-methoxybenzene (66037-03-4) + acetic anhydride (108-24-7) + 2-methoxy-phenol (90-05-1) → 6-chloroacetoguaiacone (69240-98-8) + 4-chloroguaiacol acetate (85430-09-7)

Guidance literature:

acetic anhydride; 2-methoxy-phenol; With sulfuric acid; In acetic anhydride; for 0.5h; refluxing;

2-methoxyphenyl acetate; With sulfuryl dichloride; In chloroform; at 20 ℃; for 24h;

2-acetoxy-4-chloro-1-methoxybenzene; With aluminium trichloride; at 100 ℃; for 1h; heating on boiling water bath;

DOI:10.1016/0045-6535(94)00448-4

upstream raw materials:

2-methoxyphenyl acetate

2-acetoxy-4-chloro-1-methoxybenzene

acetic anhydride

2-methoxy-phenol

Refernces