<2-Methylcinnamoyl(methoxycarbonyl)methylene>triphenylphosphorane

Base Information

• Chemical Name: <2-Methylcinnamoyl(methoxycarbonyl)methylene>triphenylphosphorane
• CAS No.: 167561-53-7
• Molecular Formula: C₃₁H₂₇O₃P
• Molecular Weight: 478.527
• Mol file: 167561-53-7.mol

Synonyms:<2-Methylcinnamoyl(methoxycarbonyl)methylene>triphenylphosphorane

Chemical Property of <2-Methylcinnamoyl(methoxycarbonyl)methylene>triphenylphosphorane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <2-Methylcinnamoyl(methoxycarbonyl)methylene>triphenylphosphorane

There total 4 articles about <2-Methylcinnamoyl(methoxycarbonyl)methylene>triphenylphosphorane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

methyl (triphenylphosphoranylidene)acetate (21204-67-1,2605-67-6) + (E)‐3‐(o‐tolyl)acryloyl chloride (83612-52-6) → <2-Methylcinnamoyl(methoxycarbonyl)methylene>triphenylphosphorane (167561-53-7)

Guidance literature:

DOI:10.1016/0040-4039(94)02445-H

Reference yield:

(E)-3-(2-methylphenyl)acrylic acid (939-57-1,2373-76-4,41397-71-1) → <2-Methylcinnamoyl(methoxycarbonyl)methylene>triphenylphosphorane (167561-53-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / SOCl₂ / 2 h / Heating

2: 77 percent / toluene / 2 h / 40 °C

With thionyl chloride; In toluene;

Reference yield:

ethyl trans-2-methylcinnamate (24393-48-4) → <2-Methylcinnamoyl(methoxycarbonyl)methylene>triphenylphosphorane (167561-53-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 69 percent / 2 M aq. NaOH / 2.5 h / Heating

2: 89 percent / SOCl₂ / 2 h / Heating

3: 77 percent / toluene / 2 h / 40 °C

With sodium hydroxide; thionyl chloride; In toluene;

upstream raw materials:

methyl (triphenylphosphoranylidene)acetate

(E)‐3‐(o‐tolyl)acryloyl chloride

(E)-3-(2-methylphenyl)acrylic acid

ethyl trans-2-methylcinnamate

Downstream raw materials:

methanol

2-ethylnaphthalene

2-naphthylethylene

2-Methylnaphthalene