Technology Process of 4-allyldimethylsilylphenethyl alcohol
There total 3 articles about 4-allyldimethylsilylphenethyl alcohol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-allyldimethylsilyl-4-bromobenzene;
With
tert.-butyl lithium;
In
tetrahydrofuran; Petroleum ether;
at 20 ℃;
for 1h;
oxirane;
In
tetrahydrofuran;
at -78 - 20 ℃;
for 0.5h;
DOI:10.1016/S0040-4020(01)00457-4
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C
1.2: 82 percent / tetrahydrofuran / 1 h / 20 °C
2.1: t-BuLi / tetrahydrofuran; petroleum ether / 1 h / 20 °C
2.2: 67 percent / tetrahydrofuran / 0.5 h / -78 - 20 °C
With
n-butyllithium; tert.-butyl lithium;
In
tetrahydrofuran; hexane; Petroleum ether;
DOI:10.1016/S0040-4020(01)00457-4
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C
1.2: 82 percent / tetrahydrofuran / 1 h / 20 °C
2.1: t-BuLi / tetrahydrofuran; petroleum ether / 1 h / 20 °C
2.2: 67 percent / tetrahydrofuran / 0.5 h / -78 - 20 °C
With
n-butyllithium; tert.-butyl lithium;
In
tetrahydrofuran; hexane; Petroleum ether;
DOI:10.1016/S0040-4020(01)00457-4
