N-(tert-butoxycarbonyl)-6-methoxyanthranilamide

Base Information

• Chemical Name: N-(tert-butoxycarbonyl)-6-methoxyanthranilamide
• CAS No.: 136247-99-9
• Molecular Formula: C₁₃H₁₈N₂O₄
• Molecular Weight: 266.297
• Mol file: 136247-99-9.mol

Synonyms:N-(tert-butoxycarbonyl)-6-methoxyanthranilamide

Chemical Property of N-(tert-butoxycarbonyl)-6-methoxyanthranilamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-(tert-butoxycarbonyl)-6-methoxyanthranilamide

There total 2 articles about N-(tert-butoxycarbonyl)-6-methoxyanthranilamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

m-Anisidine (536-90-3,918666-97-4) → N-(tert-butoxycarbonyl)-6-methoxyanthranilamide (136247-99-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / tetrahydrofuran / 48 h / 50 °C

In tetrahydrofuran;

DOI:10.1021/jo00023a036

Reference yield:

carbon dioxide (124-38-9,18923-20-1) + tert-butyl 3-methoxyphenylcarbamate (60144-52-7) → N-(tert-butoxycarbonyl)-6-methoxyanthranilamide (136247-99-9)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1021/jo00023a036

Reference yield: 95.0%

N-(tert-butoxycarbonyl)-6-methoxyanthranilamide (136247-99-9) → 2-amino-6-methoxybenzamide (1591-38-4)

Guidance literature:

With hydrogenchloride; In acetic acid; for 2h; Ambient temperature;

DOI:10.1021/jo00023a036

upstream raw materials:

carbon dioxide

tert-butyl 3-methoxyphenylcarbamate

m-Anisidine

Downstream raw materials:

2-amino-6-methoxybenzamide

6-hydroxyanthranilamide