4,6-bis(trimethylsilyloxy)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine

Base Information

• Chemical Name: 4,6-bis(trimethylsilyloxy)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine
• CAS No.: 1021424-64-5
• Molecular Formula: C₂₁H₂₆N₄O₃Si₂
• Molecular Weight: 438.633
• Mol file: 1021424-64-5.mol

Synonyms:4,6-bis(trimethylsilyloxy)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine

Chemical Property of 4,6-bis(trimethylsilyloxy)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,6-bis(trimethylsilyloxy)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine

There total 1 articles about 4,6-bis(trimethylsilyloxy)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) + 1,8-dihydroxy-9-phenyl-9H-2,4,5,7-tetraazaxanthene (155375-99-8) → 4,6-bis(trimethylsilyloxy)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine (1021424-64-5)

Guidance literature:

With ammonium sulfate; Heating;

DOI:10.1134/S1070363207040159

Reference yield: 57.0%

4,6-bis(trimethylsilyloxy)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine (1021424-64-5) + β-D-glucose pentaacetate (604-69-3) → 3-(β-D-glucopyranosyl)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine-4,6(3H,7H)-dione

Guidance literature:

4,6-bis(trimethylsilyloxy)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine; β-D-glucose pentaacetate; With tin(IV) chloride; In dichloromethane; at 18 - 20 ℃; for 72h;

With methanol; In dichloromethane; at 60 ℃; for 0.25h;

With hydrogenchloride; In methanol; at 18 - 20 ℃; for 12h; Further stages.;

DOI:10.1134/S1070363207040159

Reference yield: 31.0%

4,6-bis(trimethylsilyloxy)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine (1021424-64-5) + 1,2,3,5-tetraacetylribose (13035-61-5) → 3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine-4,6(3H,7H)-dione (1021424-65-6) + 3,7-bis(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine-4,6(3H,7H)-dione

Guidance literature:

4,6-bis(trimethylsilyloxy)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine; 1,2,3,5-tetraacetylribose; With tin(IV) chloride; In dichloromethane; at 18 - 20 ℃; for 15h;

With methanol; In dichloromethane; at 60 ℃; for 0.25h; Further stages.;

DOI:10.1134/S1070363207040159

upstream raw materials:

1,1,1,3,3,3-hexamethyl-disilazane

1,8-dihydroxy-9-phenyl-9H-2,4,5,7-tetraazaxanthene

Downstream raw materials:

3,7-bis(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine-4,6(3H,7H)-dione

3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-5-phenyl-5H-pyrano[2,3-d:6,5-d']dipyrimidine-4,6(3H,7H)-dione