2'-hydroxy-5'-phenylchalcone

Base Information

Chemical Name:2'-hydroxy-5'-phenylchalcone
CAS No.:128961-15-9
Molecular Formula:C₂₁H₁₆O₂
Molecular Weight:300.357
Hs Code.:

Synonyms:2'-hydroxy-5'-phenylchalcone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2'-hydroxy-5'-phenylchalcone

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Technology Process of 2'-hydroxy-5'-phenylchalcone

There total 2 articles about 2'-hydroxy-5'-phenylchalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 14031-80-2
2-hydroxy-5-phenylacetophenone

: 100-52-7
benzaldehyde

: 128961-15-9
2'-hydroxy-5'-phenylchalcone

Guidance literature:: With potassium hydroxide; In ethanol; at 50 - 60 ℃; for 3h;
DOI:10.1246/bcsj.56.2037

Reference yield:

: 92-69-3
4-Phenylphenol

: 128961-15-9
2'-hydroxy-5'-phenylchalcone

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / BF₃ / 2 h / Heating

2: 73 percent / 60percent aq. KOH / ethanol / 3 h / 50 - 60 °C

With potassium hydroxide; boron trifluoride; In ethanol;
DOI:10.1246/bcsj.56.2037