1-O-<(tert-butyl)dimethylsilyl>-2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-α-D-ribofuranose

Base Information

• Chemical Name: 1-O-<(tert-butyl)dimethylsilyl>-2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-α-D-ribofuranose
• CAS No.: 130472-44-5
• Molecular Formula: C₃₂H₄₂O₆Si
• Molecular Weight: 550.767

Synonyms:1-O-<(tert-butyl)dimethylsilyl>-2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-α-D-ribofuranose

Chemical Property of 1-O-<(tert-butyl)dimethylsilyl>-2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-α-D-ribofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-O-<(tert-butyl)dimethylsilyl>-2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-α-D-ribofuranose

There total 2 articles about 1-O-<(tert-butyl)dimethylsilyl>-2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-α-D-ribofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-D-ribofuranose (130472-43-4,130500-51-5) + tert-butyldimethylsilyl chloride (18162-48-6) → 3-O-<(tert-butyl)dimethylsilyl>-2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-α/β-D-ribofuranose (130472-46-7,130472-47-8) + 1,3-bis-O-<(tert-butyl)dimethylsilyl>-2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-α/β-D-ribofuranose (130472-48-9,130472-49-0) + 1-O-<(tert-butyl)dimethylsilyl>-2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-α-D-ribofuranose (130472-44-5) + 1-O-<(tert-butyl)dimethylsilyl>-2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-β-D-ribofuranose (130472-45-6)

Guidance literature:

With pyridine; silver nitrate; In tetrahydrofuran; for 3h; Ambient temperature;

DOI:10.1002/hlca.19900730309

Reference yield:

2-deoxy-D-ribose (22900-10-3,35536-75-5,36792-85-5,113890-34-9,113890-37-2,133813-23-7) → 1-O-<(tert-butyl)dimethylsilyl>-2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-α-D-ribofuranose (130472-44-5)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 4 h

2: 30 percent / pyridine / 1 h / 0 °C

With pyridine;

DOI:10.1002/hlca.19900730309

Reference yield: 94.0%

N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite (102691-36-1) + 1-O-<(tert-butyl)dimethylsilyl>-2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-α-D-ribofuranose (130472-44-5) → 1-O-<(tert-butyl)dimethylsilyl>-3-O-<(2-cyanoethoxy)(N,N-diisopropylamino)phosphino>-2-deoxy-α-D-ribofuranose (130472-50-3,130472-57-0)

Guidance literature:

With N,N-diisopropylamine tetrazolide; In dichloromethane; for 1h; Ambient temperature;

DOI:10.1002/hlca.19900730309

upstream raw materials:

2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-D-ribofuranose

tert-butyldimethylsilyl chloride

2-deoxy-D-ribose

Downstream raw materials:

1-O-<(tert-butyl)dimethylsilyl>-3-O-<(2-cyanoethoxy)(N,N-diisopropylamino)phosphino>-2-deoxy-α-D-ribofuranose

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 130472-44-5 1-O-<(tert-butyl)dimethylsilyl>-2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-α-D-ribofuranose

Send

Send

Metric Ton KG G Pound L ML

Send

Send