Ethyl 3,4-dimethoxy-alpha-(methylthio)-alpha-phenylbenzeneacetate

Base Information

Chemical Name:Ethyl 3,4-dimethoxy-alpha-(methylthio)-alpha-phenylbenzeneacetate
CAS No.:97611-70-6
Molecular Formula:C₁₉H₂₂O₄S
Molecular Weight:346.447
Hs Code.:
DSSTox Substance ID:DTXSID801196252

Synonyms:DTXSID801196252;Ethyl 3,4-dimethoxy-alpha-(methylthio)-alpha-phenylbenzeneacetate;97611-70-6

Suppliers and Price of Ethyl 3,4-dimethoxy-alpha-(methylthio)-alpha-phenylbenzeneacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ethyl 3,4-dimethoxy-alpha-(methylthio)-alpha-phenylbenzeneacetate

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:346.12388035
Heavy Atom Count:24
Complexity:397

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C(C1=CC=CC=C1)(C2=CC(=C(C=C2)OC)OC)SC

Technology Process of Ethyl 3,4-dimethoxy-alpha-(methylthio)-alpha-phenylbenzeneacetate

There total 2 articles about Ethyl 3,4-dimethoxy-alpha-(methylthio)-alpha-phenylbenzeneacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 91-16-7
1,2-dimethoxybenzene

: Chloro-methylsulfanyl-phenyl-acetic acid ethyl ester

: 97611-70-6
ethyl α-methylthio-α-phenyl-3,4-dimethoxyphenylacetate

Guidance literature:: With tin(IV) chloride; In dichloromethane; at 0 ℃; for 1h; Yield given;
DOI:10.1248/cpb.33.340

Reference yield:

: 75280-06-7
ethyl α-(methylthio)phenylacetate

: 97611-70-6
ethyl α-methylthio-α-phenyl-3,4-dimethoxyphenylacetate

Guidance literature:: Multi-step reaction with 2 steps

1: N-chlorosuccinimide / CCl₄ / 1.5 h / 0 °C

2: SnCl₄ / CH₂Cl₂ / 1 h / 0 °C

With N-chloro-succinimide; tin(IV) chloride; In tetrachloromethane; dichloromethane;
DOI:10.1248/cpb.33.340