p-cyano-α-chlorocumene

Base Information

• Chemical Name: p-cyano-α-chlorocumene
• CAS No.: 72206-85-0
• Molecular Formula: C₁₀H₁₀ClN
• Molecular Weight: 179.649
• Mol file: 72206-85-0.mol

Synonyms:p-cyano-α-chlorocumene

Chemical Property of p-cyano-α-chlorocumene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-cyano-α-chlorocumene

There total 1 articles about p-cyano-α-chlorocumene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(2-hydroxypropan-2-yl)benzenecarbonitrile (77802-22-3) → p-cyano-α-chlorocumene (72206-85-0)

Guidance literature:

With hydrogenchloride; dichloromethane;

DOI:10.1021/ja01551a052

Reference yield: 86.0%

p-cyano-α-chlorocumene (72206-85-0) → 2-(p-cyanophenyl)-2-methyl-3-nitrobutane (65253-36-3)

Guidance literature:

In N,N,N,N,N,N-hexamethylphosphoric triamide; at 25 ℃; Irradiation;

DOI:10.1021/jo01290a036

Reference yield: 86.0%

p-cyano-α-chlorocumene (72206-85-0) + lithium 1-nitroethan-1-ide (28735-55-9) → 2-(p-cyanophenyl)-2-methyl-3-nitrobutane (65253-36-3)

Guidance literature:

In N,N,N,N,N,N-hexamethylphosphoric triamide; for 24h; Ambient temperature; Irradiation;

DOI:10.1016/0040-4020(89)80129-2

upstream raw materials:

4-(2-hydroxypropan-2-yl)benzenecarbonitrile

Downstream raw materials:

2-(4-cyanophenyl)propene

2-(4-nitrophenyl)propan-2-ol

2-(p-cyanophenyl)-4-nitropentane

2-(p-cyanophenyl)-2-methyl-3-nitrobutane