3,12-diethynyl-6,9-dimethoxy-1,14-bis(trimethylsilyl)-6,9-diphenyltetradeca-1,4,7,10,13-pentayne-3,12-diol

Base Information

• Chemical Name: 3,12-diethynyl-6,9-dimethoxy-1,14-bis(trimethylsilyl)-6,9-diphenyltetradeca-1,4,7,10,13-pentayne-3,12-diol
• CAS No.: 945393-17-9
• Molecular Formula: C₃₈H₃₈O₄Si₂
• Molecular Weight: 614.888
• Mol file: 945393-17-9.mol

Synonyms:3,12-diethynyl-6,9-dimethoxy-1,14-bis(trimethylsilyl)-6,9-diphenyltetradeca-1,4,7,10,13-pentayne-3,12-diol

Chemical Property of 3,12-diethynyl-6,9-dimethoxy-1,14-bis(trimethylsilyl)-6,9-diphenyltetradeca-1,4,7,10,13-pentayne-3,12-diol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,12-diethynyl-6,9-dimethoxy-1,14-bis(trimethylsilyl)-6,9-diphenyltetradeca-1,4,7,10,13-pentayne-3,12-diol

There total 2 articles about 3,12-diethynyl-6,9-dimethoxy-1,14-bis(trimethylsilyl)-6,9-diphenyltetradeca-1,4,7,10,13-pentayne-3,12-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

6,9-dimethoxy-1,14-bis(trimethylsilyl)-6,9-diphenyltetradeca-1,4,7,10,13-pentayne-3,12-dione + acetylenemagnesium bromide (4301-14-8) → 3,12-diethynyl-6,9-dimethoxy-1,14-bis(trimethylsilyl)-6,9-diphenyltetradeca-1,4,7,10,13-pentayne-3,12-diol (945393-17-9)

Guidance literature:

In tetrahydrofuran; at 0 - 20 ℃; for 4h;

DOI:10.1002/chem.200601191

Reference yield:

1,14-bis(trimethylsily)-6,9-dimethoxy-6,9-diphenyltetradeca-1,4,7,10,13-pentayne-3,12-diol (945393-05-5) → 3,12-diethynyl-6,9-dimethoxy-1,14-bis(trimethylsilyl)-6,9-diphenyltetradeca-1,4,7,10,13-pentayne-3,12-diol (945393-17-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / manganese oxide / CH₂Cl₂ / 1 h / 20 °C

2: 71 percent / tetrahydrofuran / 4 h / 0 - 20 °C

With manganese oxide; In tetrahydrofuran; dichloromethane;

DOI:10.1002/chem.200601191

Reference yield: 80.0%

3,12-diethynyl-6,9-dimethoxy-1,14-bis(trimethylsilyl)-6,9-diphenyltetradeca-1,4,7,10,13-pentayne-3,12-diol (945393-17-9) + methyl iodide (74-88-4) → 3,12-diethynyl-3,6,9,12-tetramethoxy-1,14-bis(trimethylsilyl)-6,9-diphenyltetradeca-1,4,7,10,13-pentayne

Guidance literature:

3,12-diethynyl-6,9-dimethoxy-1,14-bis(trimethylsilyl)-6,9-diphenyltetradeca-1,4,7,10,13-pentayne-3,12-diol; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.333333h;

methyl iodide; In tetrahydrofuran; hexane; dimethyl sulfoxide; at 20 ℃; for 17h; Further stages.;

DOI:10.1002/chem.200601191

upstream raw materials:

acetylenemagnesium bromide

1,14-bis(trimethylsily)-6,9-dimethoxy-6,9-diphenyltetradeca-1,4,7,10,13-pentayne-3,12-diol