6-(4-Nitrophenyl)pyridine-2-carboxylic acid

Base Information

Chemical Name:6-(4-Nitrophenyl)pyridine-2-carboxylic acid
CAS No.:80021-26-7
Molecular Formula:C12H8 N2 O4
Molecular Weight:0
Hs Code.:
DSSTox Substance ID:DTXSID00510472
Wikidata:Q82368784
Mol file:80021-26-7.mol

Synonyms:80021-26-7;6-(4-nitrophenyl)picolinic acid;6-(4-Nitrophenyl)pyridine-2-carboxylic acid;2-Pyridinecarboxylicacid, 6-(4-nitrophenyl)-;SCHEMBL11155807;DTXSID00510472;F96286

Suppliers and Price of 6-(4-Nitrophenyl)pyridine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 6-(4-Nitrophenyl)pyridine-2-carboxylic acid

Chemical Property:

PSA：96.01000
LogP:2.87820
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:244.04840674
Heavy Atom Count:18
Complexity:321

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC(=C1)C(=O)O)C2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of 6-(4-Nitrophenyl)pyridine-2-carboxylic acid

There total 3 articles about 6-(4-Nitrophenyl)pyridine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4282-47-7
2-(4-nitrophenyl)pyridine

: 80021-26-7
6-(4-nitrophenyl)-2-pyridinecarboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 30percent aq. H₂O₂ / acetic acid / 20 h / 80 °C

2: 1.) Me₂SO₄ / 1.) 80-90 deg C, 2 h, 2.) dioxane, H₂O, RT, 30 min

3: 5 M aq. HCl / 11 h / Heating

With hydrogenchloride; dihydrogen peroxide; dimethyl sulfate; In acetic acid;
DOI:10.1021/jm00364a026

Reference yield:

: 6-(4-Nitro-phenyl)-pyridine-2-carbonitrile

: 80021-26-7
6-(4-nitrophenyl)-2-pyridinecarboxylic acid

Guidance literature:: With hydrogenchloride; for 11h; Heating;
DOI:10.1021/jm00364a026

Reference yield:

: 84794-09-2
2-(p-nitrophenyl)pyridine N-oxide

: 80021-26-7
6-(4-nitrophenyl)-2-pyridinecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Me₂SO₄ / 1.) 80-90 deg C, 2 h, 2.) dioxane, H₂O, RT, 30 min

2: 5 M aq. HCl / 11 h / Heating

With hydrogenchloride; dimethyl sulfate;
DOI:10.1021/jm00364a026