N-allyl-3-methylindole

Base Information

• Chemical Name: N-allyl-3-methylindole
• CAS No.: 1914-05-2
• Molecular Formula: C₁₂H₁₃N
• Molecular Weight: 171.242
• Mol file: 1914-05-2.mol

Synonyms:N-allyl-3-methylindole

Chemical Property of N-allyl-3-methylindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-allyl-3-methylindole

There total 6 articles about N-allyl-3-methylindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

3-Methylindole (83-34-1) + allyl bromide (106-95-6) → N-allyl-3-methylindole (1914-05-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 10h; regioselective reaction;

DOI:10.1016/j.catcom.2015.07.022

Reference yield: 84.0%

2-iodo-N,N-diallylaniline (73396-92-6) → 1-allyl-3-(p-methoxybenzoylmethyl)indoline + N-allyl-3-methylindole (1914-05-2)

Guidance literature:

With tris-(o-tolyl)phosphine; palladium diacetate; In toluene; at 20 ℃; for 24h;

DOI:10.1246/bcsj.78.331

Reference yield: 82.0%

3-Methylindole (83-34-1) + Allyl acetate (591-87-7) → N-allyl-3-methylindole (1914-05-2)

Guidance literature:

With palladium(II) trifluoroacetate; trifuran-2-yl-phosphane; In water; for 3h; Reflux; Inert atmosphere; Green chemistry;

DOI:10.1039/c9nj02335f

upstream raw materials:

3-Methylindole

allyl bromide

2-iodo-N,N-diallylaniline

Allyl acetate

Downstream raw materials:

2-propyl-3-methylindole

3-(carbomethoxymethyl)-3,4-dihydro-10-methyl-1-phenylpyrazino<1,2-a>indole

cis-1,2,3,4-tetrahydro-1-phenyl-3,10-dimethylpyrazino<1,2-a>indole

benzylamine