Technology Process of C17H16O4
There total 3 articles about C17H16O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-(tert-butyloxycarbonyl)-L-isoleucine; [bis(acetoxy)iodo]benzene; potassium acetate; palladium diacetate;
In
tert-butyl alcohol;
at 70 ℃;
for 24h;
enantioselective reaction;
Sealed tube;
DOI:10.1021/ja311259x
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: iron(III) chloride / dichloromethane / -10 °C / Inert atmosphere
2.1: sodium hydroxide / methanol / 24 h / Reflux
2.2: 0 °C
3.1: N-(tert-butyloxycarbonyl)-L-isoleucine; palladium diacetate; potassium acetate; [bis(acetoxy)iodo]benzene / tert-butyl alcohol / 24 h / 70 °C / Sealed tube
With
iron(III) chloride; N-(tert-butyloxycarbonyl)-L-isoleucine; [bis(acetoxy)iodo]benzene; potassium acetate; palladium diacetate; sodium hydroxide;
In
methanol; dichloromethane; tert-butyl alcohol;
DOI:10.1021/ja311259x
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydroxide / methanol / 24 h / Reflux
1.2: 0 °C
2.1: N-(tert-butyloxycarbonyl)-L-isoleucine; palladium diacetate; potassium acetate; [bis(acetoxy)iodo]benzene / tert-butyl alcohol / 24 h / 70 °C / Sealed tube
With
N-(tert-butyloxycarbonyl)-L-isoleucine; [bis(acetoxy)iodo]benzene; potassium acetate; palladium diacetate; sodium hydroxide;
In
methanol; tert-butyl alcohol;
DOI:10.1021/ja311259x
