93652-65-4Relevant academic research and scientific papers
Palladium(II)-Catalyzed C(sp2)-H Carbonylation of Sterically Hindered Amines with Carbon Monoxide
Cheng, Xiu-Fen,Wang, Tao,Li, Yan,Wu, Yun,Sheng, Jie,Wang, Rui,Li, Chao,Bian, Kang-Jie,Wang, Xi-Sheng
supporting information, p. 6530 - 6533 (2018/10/20)
A palladium-catalyzed, amine-directed C(sp2)-H carbonylation of α,α-disubstituted benzylamine under 1 atm of CO for the facile synthesis of sterically hindered benzolactam has been developed. The key to success is the use of 2,2,6,6-tetramethyl-1-piperidinyloxy as the crucial sole oxidant. The synthetic utility of this transformation has been demonstrated by the first concise synthesis of the natural product spiropachysin-20-one.
Pd(II)-catalyzed enantioselective C-H activation/C-O bond formation: Synthesis of chiral benzofuranones
Cheng, Xiu-Fen,Li, Yan,Su, Yi-Ming,Yin, Feng,Wang, Jian-Yong,Sheng, Jie,Vora, Harit U.,Wang, Xi-Sheng,Yu, Jin-Quan
, p. 1236 - 1239 (2013/03/14)
Pd(II)-catalyzed enantioselective C-H activation of phenylacetic acids followed by an intramolecular C-O bond formation afforded chiral benzofuranones. This reaction provides the first example of enantioselecctive C-H functionalizations through Pd(II)/Pd(IV) redox catalysis.
Room-temperature bismuth-catalyzed bis-arylation of carbonyl compounds with aryl ethers and phenols
Liu, Congrong,Li, Manbo
, p. 1274 - 1278 (2013/11/06)
Using Bi2(SO4)3 as the catalyst and TMSCl as the additive, a wide variety of aldehydes, ketones, and acetals were smoothly condensed with aryl ethers at room temperature to provide the corresponding diarylmethanes and triarylmethanes selectively in good to excellent yields. Using Bi2(SO4)3 as the catalyst and TMSCl as the additive, a wide variety of aldehydes, ketones, and acetals were smoothly condensed with aryl ethers at room temperature to selectively provide the corresponding diarylmethanes and triarylmethanes in good to excellent yields. Copyright
Acid-mediated specific α,α-diarylation and α-monoarylation reactions of pyruvic acid with/without decarbonylation
Yonezawa, Noriyuki,Hino, Tetsuo,Kinuno, Tsuyoshi,Matsuki, Toshiyuki,Ikeda, Tomiki
, p. 1687 - 1695 (2007/10/03)
Pyruvic acid (3) was found to be arylated chemoselectively at the α- ketocarbonyl carbon in P2O5-MsOH affording decarbonylative α,α-diarylated products 5, decarbonylative α-monoarylated compounds 6, or non- decarbonylative α,α-diarylated adducts 7 depending on the reactivity of arenes (4a-g), in contrast to Lewis acid-catalyzed reaction of its acid chloride (2).
