2,3,4-tri-O-benzyl-1-deoxy-1-(4-methoxybenzylamino)-D-xylose

Base Information

• Chemical Name: 2,3,4-tri-O-benzyl-1-deoxy-1-(4-methoxybenzylamino)-D-xylose
• CAS No.: 1222827-00-0
• Molecular Formula: C₃₄H₃₇NO₅
• Molecular Weight: 539.671
• Mol file: 1222827-00-0.mol

Synonyms:2,3,4-tri-O-benzyl-1-deoxy-1-(4-methoxybenzylamino)-D-xylose

Chemical Property of 2,3,4-tri-O-benzyl-1-deoxy-1-(4-methoxybenzylamino)-D-xylose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4-tri-O-benzyl-1-deoxy-1-(4-methoxybenzylamino)-D-xylose

There total 1 articles about 2,3,4-tri-O-benzyl-1-deoxy-1-(4-methoxybenzylamino)-D-xylose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,4-tri-O-benzyl-D-xylopyranose (18039-26-4,20787-16-0,20787-21-7,77943-32-9,77943-33-0,89615-43-0,89615-44-1,90899-55-1) + 4-methoxy-benzylamine (2393-23-9) → 2,3,4-tri-O-benzyl-1-deoxy-1-(4-methoxybenzylamino)-D-xylose (1222827-00-0)

Guidance literature:

With camphor-10-sulfonic acid; sodium sulfate; In toluene; for 2.5h; Reflux;

DOI:10.1002/ejoc.200901208

Reference yield: 97.0%

2,3,4-tri-O-benzyl-1-deoxy-1-(4-methoxybenzylamino)-D-xylose (1222827-00-0) + allylmagnesium bromide (1730-25-2) → 2,3,4-tri-O-benzyl-1-deoxy-1-[(4-methoxybenzyl)amino]-1-C-(prop-2-enyl)-D-xylitol

Guidance literature:

In tetrahydrofuran; at 0 - 20 ℃; for 16h;

DOI:10.1002/ejoc.200901208

Reference yield: 86.0%

2,3,4-tri-O-benzyl-1-deoxy-1-(4-methoxybenzylamino)-D-xylose (1222827-00-0) + vinyl magnesium bromide (1826-67-1) → (2R,3R,4S,5R)-2,3,4-tris(benzyloxy)-5-(4-methoxybenzylamino)-hept-6-en-1-ol (1363300-61-1)

Guidance literature:

In tetrahydrofuran; diethyl ether; at 0 - 20 ℃; for 2h;

DOI:10.1021/jm201633y

upstream raw materials:

2,3,4-tri-O-benzyl-D-xylopyranose

4-methoxy-benzylamine

Downstream raw materials:

(2R,3S,4S,5R)-3,4,5-tris(benzyloxy)-1-(4-methoxybenzyl)-2-vinyl-piperidine

(2R,3S,4S,5R)-3,4,5-tris(benzyloxy)-2-vinyl-piperidine

3,4-di-O-benzyl-N-benzylcarboyl-1,2,6-trideoxy-1,5-imino-6-C-vinyl-D-iditol

(2R,3R,4S,5R)-2,3,4-tris(benzyloxy)-5-(4-methoxybenzylamino)-hept-6-en-1-ol