{2-[3,3,3-tris-(4-chloro-phenyl)-propionylamino]-acetylamino}-acetic acid undec-10-enyl ester

Base Information

• Chemical Name: {2-[3,3,3-tris-(4-chloro-phenyl)-propionylamino]-acetylamino}-acetic acid undec-10-enyl ester
• CAS No.: 556810-28-7
• Molecular Formula: C₃₆H₄₁Cl₃N₂O₄
• Molecular Weight: 672.092
• Mol file: 556810-28-7.mol

Synonyms:{2-[3,3,3-tris-(4-chloro-phenyl)-propionylamino]-acetylamino}-acetic acid undec-10-enyl ester

Chemical Property of {2-[3,3,3-tris-(4-chloro-phenyl)-propionylamino]-acetylamino}-acetic acid undec-10-enyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {2-[3,3,3-tris-(4-chloro-phenyl)-propionylamino]-acetylamino}-acetic acid undec-10-enyl ester

There total 3 articles about {2-[3,3,3-tris-(4-chloro-phenyl)-propionylamino]-acetylamino}-acetic acid undec-10-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

10-Undecen-1-ol (112-43-6) + N-((tris(4-chlorophenyl)propionyl)glycyl)glycine ethyl ester (556810-25-4) → {2-[3,3,3-tris-(4-chloro-phenyl)-propionylamino]-acetylamino}-acetic acid undec-10-enyl ester (556810-28-7)

Guidance literature:

With 1,3-dichlorotetrabutyldistannoxane; In toluene; for 1h; Heating;

DOI:10.1021/ol0344927

Reference yield:

3,3,3-Tris(4-chlorophenyl)-propionic acid (2168-06-1) → {2-[3,3,3-tris-(4-chloro-phenyl)-propionylamino]-acetylamino}-acetic acid undec-10-enyl ester (556810-28-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 90 percent / oxalyl chloride / toluene / 24 h / 20 °C

2: 30 percent / triethylamine / CH₂Cl₂ / 18 h

3: 97 percent / bis(dibutylchlorotin)oxide / toluene / 1 h / Heating

With oxalyl dichloride; 1,3-dichlorotetrabutyldistannoxane; triethylamine; In dichloromethane; toluene;

DOI:10.1021/ol0344927

Reference yield:

3,3,3-tris(4-chlorophenyl)propanoyl chloride (2172-49-8) → {2-[3,3,3-tris-(4-chloro-phenyl)-propionylamino]-acetylamino}-acetic acid undec-10-enyl ester (556810-28-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 30 percent / triethylamine / CH₂Cl₂ / 18 h

2: 97 percent / bis(dibutylchlorotin)oxide / toluene / 1 h / Heating

With 1,3-dichlorotetrabutyldistannoxane; triethylamine; In dichloromethane; toluene;

DOI:10.1021/ol0344927

upstream raw materials:

10-Undecen-1-ol

N-((tris(4-chlorophenyl)propionyl)glycyl)glycine ethyl ester

3,3,3-Tris(4-chlorophenyl)-propionic acid

3,3,3-tris(4-chlorophenyl)propanoyl chloride