[2-(6-amino-9-benzyl-9H-purin-8-ylamino)-ethyl]-phosphonic acid

Base Information

• Chemical Name: [2-(6-amino-9-benzyl-9H-purin-8-ylamino)-ethyl]-phosphonic acid
• CAS No.: 213247-64-4
• Molecular Formula: C₁₄H₁₇N₆O₃P
• Molecular Weight: 348.301
• Mol file: 213247-64-4.mol

Synonyms:[2-(6-amino-9-benzyl-9H-purin-8-ylamino)-ethyl]-phosphonic acid

Chemical Property of [2-(6-amino-9-benzyl-9H-purin-8-ylamino)-ethyl]-phosphonic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of [2-(6-amino-9-benzyl-9H-purin-8-ylamino)-ethyl]-phosphonic acid

There total 2 articles about [2-(6-amino-9-benzyl-9H-purin-8-ylamino)-ethyl]-phosphonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(2-aminethyl)phosphonic acid (2041-14-7) + 9-benzyl-8-bromo-9H-purin-6-amine (56046-34-5) → [2-(6-amino-9-benzyl-9H-purin-8-ylamino)-ethyl]-phosphonic acid (213247-64-4)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; sodium hydroxide; In ethanol; water; for 18h; Inert atmosphere; Reflux;

DOI:10.1021/jm900078f

Reference yield:

aminoethylphosphonate (16540-41-3) + 9-benzyl-8-bromo-9H-purin-6-amine (56046-34-5) → [2-(6-amino-9-benzyl-9H-purin-8-ylamino)-ethyl]-phosphonic acid (213247-64-4)

Guidance literature:

With sodium hydroxide; In water ethanol;

upstream raw materials:

aminoethylphosphonate

9-benzyl-8-bromo-9H-purin-6-amine

(2-aminethyl)phosphonic acid