7-Phenylbicyclo[4.1.0]heptane

Base Information

• Chemical Name: 7-Phenylbicyclo[4.1.0]heptane
• CAS No.: 1132-24-7
• Molecular Formula: C13H16
• Molecular Weight: 172.27
• NSC Number: 133261
• DSSTox Substance ID: DTXSID40299850
• Nikkaji Number: J2.000.122D
• Mol file: 1132-24-7.mol

Synonyms:7-phenylbicyclo[4.1.0]heptane;1132-24-7;NSC133261;DTXSID40299850;NSC-133261

Chemical Property of 7-Phenylbicyclo[4.1.0]heptane

Chemical Property:

• Vapor Pressure: 0.0187mmHg at 25°C
• Boiling Point: 261.5°C at 760 mmHg
• Flash Point: 105.4°C
• Density: 1.016g/cm³
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 172.125200510
• Heavy Atom Count: 13
• Complexity: 167

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC2C(C1)C2C3=CC=CC=C3

Technology Process of 7-Phenylbicyclo[4.1.0]heptane

There total 9 articles about 7-Phenylbicyclo[4.1.0]heptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3-methyl-11-phenyl-3,4,10,11-tetrahydro-1H,5H-pyrano<4,3-b><1,5>benzodiazepin-1-one (116761-13-8) + cyclohexene (110-83-8) → 7-phenyl-bicyclo[4.1.0]heptane (1132-24-7) + 3-methyl-3,4-dihydro-1H-pyrano[3,4-b]quinoxalin-1-one (735272-10-3)

Guidance literature:

With sodium hypochlorite; sulfuric acid; water; In acetonitrile; at 20 ℃; for 3h; pH=5;

Reference yield: 19.0%

phenyldiazomethane (908094-04-2) + cyclohexene (110-83-8) → 7-phenyl-bicyclo[4.1.0]heptane (1132-24-7) + stilbene (588-59-0)

Guidance literature:

[Ru2(CO)4(μ-OAc)2]n; In dichloromethane; at -20 ℃;

DOI:10.1016/S0040-4039(01)01221-7

Reference yield: 11.0%

Benzyl phenyl sulfone (3112-88-7) + cyclohexene (110-83-8) → 7-phenyl-bicyclo[4.1.0]heptane (1132-24-7) + 1,2,3-triphenylcyclopropane (19120-38-8) + stilbene (588-59-0)

Guidance literature:

With nickel(II) acetylacetonate; In tetrahydrofuran; at 65 ℃; for 6h;

upstream raw materials:

phenyldiazomethane

cyclohexene

benzylidene dibromide

Benzyl phenyl sulfone