4-TERT-BUTYLCALIX(7)ARENE

Base Information

• Chemical Name: 4-TERT-BUTYLCALIX(7)ARENE
• CAS No.: 84161-29-5
• Molecular Formula: C77H98 O7
• Molecular Weight: 1135.62
• Mol file: 84161-29-5.mol

Synonyms:p-tert-Butylcalix[7]arene;p-tert-Butylcalix[7]areneheptol

Chemical Property of 4-TERT-BUTYLCALIX(7)ARENE

Chemical Property:

• Refractive Index: 1.6810 (estimate)
• Boiling Point: 816.33°C (rough estimate)
• PSA: 141.61000
• Density: 1.0643 (rough estimate)
• LogP: 18.15730

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Safety Statements: S24/25:Avoid contact with skin and eyes.

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-TERT-BUTYLCALIX(7)ARENE

There total 21 articles about 4-TERT-BUTYLCALIX(7)ARENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + para-tert-butylphenol (98-54-4) → 4,4'‐oxybis(tert‐butylbenzene) (24085-65-2) + 5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene (157432-87-6,288302-11-4,288302-12-5,60705-62-6) + 5,11,17,23,29,35-hexakis(tert-butyl)-37,38,39,40,41-hexakis(hydroxy)calix[6]arene (189832-67-5,78092-53-2) + 5,11,17,23,29,35,41,47-octakis(tert-butyl)-49,50,51,52,53,54,55,56-octakis(hydroxy)calix[8]arene (68971-82-4,106750-70-3,78092-52-1) + p-tert-Butylcalix[5]arene (81475-22-1) + 5,11,17,23,29,35,41-heptakis(1,1-dimethylethyl)-43,44,45,46,47,48,49-heptahydroxy calix[7]arene (84161-29-5)

Guidance literature:

With sodium hydroxide; In 5,5-dimethyl-1,3-cyclohexadiene; for 5.5h; Dean-Stark; Inert atmosphere; Reflux;

DOI:10.15227/orgsyn.068.0243

Reference yield: 55.0%

1,3,5-Trioxan (110-88-3) + para-tert-butylphenol (98-54-4) → 5,11,17,23,29,35-hexakis(tert-butyl)-37,38,39,40,41-hexakis(hydroxy)calix[6]arene (189832-67-5,78092-53-2) + 5,11,17,23,29,35,41,47-octakis(tert-butyl)-49,50,51,52,53,54,55,56-octakis(hydroxy)calix[8]arene (68971-82-4,106750-70-3,78092-52-1) + 5,11,17,23,29,35,41-heptakis(1,1-dimethylethyl)-43,44,45,46,47,48,49-heptahydroxy calix[7]arene (84161-29-5) + 5,11,17,23,29,35,41,47,53-nonakis(1,1-dimethylethyl)-55,56,57,58,59,60,61,62,63-nonahydroxycalix[9]arene (190651-92-4)

Guidance literature:

With tin(IV) chloride; In dichloromethane; at 15 ℃; for 20.5h; Further Variations:; Solvents; Temperatures; reaction times; Product distribution;

DOI:10.1039/b608482f

Reference yield: 19.0%

2,6-bis(methoxymethyl)-para-tert-butylphenol (421546-91-0) + 4-(tert-butyl)-2,6-bis{[5-(tert-butyl)-2-hydroxyphenyl]methyl}phenol (810-52-6) → 5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene (157432-87-6,288302-11-4,288302-12-5,60705-62-6) + 5,11,17,23,29,35-hexakis(tert-butyl)-37,38,39,40,41-hexakis(hydroxy)calix[6]arene (189832-67-5,78092-53-2) + 5,11,17,23,29,35,41,47-octakis(tert-butyl)-49,50,51,52,53,54,55,56-octakis(hydroxy)calix[8]arene (68971-82-4,106750-70-3,78092-52-1) + p-tert-Butylcalix[5]arene (81475-22-1) + 5,11,17,23,29,35,41-heptakis(1,1-dimethylethyl)-43,44,45,46,47,48,49-heptahydroxy calix[7]arene (84161-29-5) + 5,11,17,23,29,35,41,47,53-nonakis(1,1-dimethylethyl)-55,56,57,58,59,60,61,62,63-nonahydroxycalix[9]arene (190651-92-4)

Guidance literature:

With ferrocenium(III) tetrafluoroborate; In dichloromethane; at 120 ℃; for 1h; Microwave irradiation;

DOI:10.1039/b813789g

upstream raw materials:

formaldehyd

para-tert-butylphenol

1,3,5-Trioxan

C₁₆₁H₁₉₆O₁₄S₇

Downstream raw materials:

C₁₆₁H₂₁₀O₁₄

5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene

5,11,17,23,29,35,41,47-octakis(tert-butyl)-49,50,51,52,53,54,55,56-octakis(hydroxy)calix[8]arene