(+/-)-6-O-benzyl-2,3-O-cyclohexylidene-4,5-O-isopropylidene-1-O-methoxymethyl-myo-inositol

Base Information

• Chemical Name: (+/-)-6-O-benzyl-2,3-O-cyclohexylidene-4,5-O-isopropylidene-1-O-methoxymethyl-myo-inositol
• CAS No.: 124516-79-6
• Molecular Formula: C₂₄H₃₄O₇
• Molecular Weight: 434.53
• Mol file: 124516-79-6.mol

Synonyms:(+/-)-6-O-benzyl-2,3-O-cyclohexylidene-4,5-O-isopropylidene-1-O-methoxymethyl-myo-inositol

Chemical Property of (+/-)-6-O-benzyl-2,3-O-cyclohexylidene-4,5-O-isopropylidene-1-O-methoxymethyl-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-6-O-benzyl-2,3-O-cyclohexylidene-4,5-O-isopropylidene-1-O-methoxymethyl-myo-inositol

There total 3 articles about (+/-)-6-O-benzyl-2,3-O-cyclohexylidene-4,5-O-isopropylidene-1-O-methoxymethyl-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

chloromethyl methyl ether (107-30-2) + (+/-)-6-O-benzyl-2,3-O-cyclohexylidene-4,5-O-isopropylidene-myo-inositol (124516-77-4) → (+/-)-6-O-benzyl-2,3-O-cyclohexylidene-4,5-O-isopropylidene-1-O-methoxymethyl-myo-inositol (124516-79-6)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; paraffin; 0 deg C, 30 min then R_.T_., 3 h;

DOI:10.1248/cpb.37.791

Reference yield:

benzyl bromide (100-39-0) → (+/-)-6-O-benzyl-2,3-O-cyclohexylidene-4,5-O-isopropylidene-1-O-methoxymethyl-myo-inositol (124516-79-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) 50percent NaH, 2.) 1N KOH / 1.) DMF, mineral oil, 0 deg C, 30 min then R_.T_., 2 h, 2.) MeOH, R_.T_., 2 h

2: 89 percent / 50percent NaH / dimethylformamide; paraffin / 0 deg C, 30 min then R_.T_., 3 h

With potassium hydroxide; sodium hydride; In N,N-dimethyl-formamide; paraffin;

DOI:10.1248/cpb.37.791

Reference yield:

(+/-)-1-O-benzoyl-2,3-O-cyclohexylidene-4,5-O-isopropylidene-myo-inositol (64290-81-9) → (+/-)-6-O-benzyl-2,3-O-cyclohexylidene-4,5-O-isopropylidene-1-O-methoxymethyl-myo-inositol (124516-79-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) 50percent NaH, 2.) 1N KOH / 1.) DMF, mineral oil, 0 deg C, 30 min then R_.T_., 2 h, 2.) MeOH, R_.T_., 2 h

2: 89 percent / 50percent NaH / dimethylformamide; paraffin / 0 deg C, 30 min then R_.T_., 3 h

With potassium hydroxide; sodium hydride; In N,N-dimethyl-formamide; paraffin;

DOI:10.1248/cpb.37.791

upstream raw materials:

chloromethyl methyl ether

(+/-)-6-O-benzyl-2,3-O-cyclohexylidene-4,5-O-isopropylidene-myo-inositol

benzyl bromide

(+/-)-1-O-benzoyl-2,3-O-cyclohexylidene-4,5-O-isopropylidene-myo-inositol

Downstream raw materials:

C₂₁H₃₀O₇

(+/-)-6-O-benzyl-2,3-O-cyclohexylidene-1,4-di-O-methoxymethyl-myo-inositol

C₃₄H₄₈O₁₅

C₃₄H₄₈O₁₅