Technology Process of 24-oxo-3β-cholesteryl benzoate
There total 5 articles about 24-oxo-3β-cholesteryl benzoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
5α,6β-dibromocholestan-3β-yl benzoate;
With
[bis(acetoxy)iodo]benzene; water; [RuCl(2-(bis(pyridin-2-ylmethyl)amino)-N-(2,6-dimethylphenyl)acetamide)(PPh3)]Cl;
at 30 ℃;
for 24h;
Sealed tube;
Inert atmosphere;
With
acetic anhydride; zinc;
In
diethyl ether;
at 20 ℃;
for 4.5h;
Inert atmosphere;
DOI:10.3390/molecules27010225
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dmap; triethylamine / dichloromethane / 23.5 h / 0 - 20 °C / Inert atmosphere
2.1: potassium acetate; bromine / diethyl ether; acetic acid / 3 h / 0 °C / Inert atmosphere
3.1: [RuCl(2-(bis(pyridin-2-ylmethyl)amino)-N-(2,6-dimethylphenyl)acetamide)(PPh3)]Cl; [bis(acetoxy)iodo]benzene; water / 24 h / 30 °C / Sealed tube; Inert atmosphere
3.2: 4.5 h / 20 °C / Inert atmosphere
With
dmap; [bis(acetoxy)iodo]benzene; water; bromine; potassium acetate; [RuCl(2-(bis(pyridin-2-ylmethyl)amino)-N-(2,6-dimethylphenyl)acetamide)(PPh3)]Cl; triethylamine;
In
diethyl ether; dichloromethane; acetic acid;
DOI:10.3390/molecules27010225
