26048-47-5

Upstream product

• 6585-67-7 3β-benzoyloxy-5-bromo-5α-cholestan-6β-ol 
• 34048-78-7 3β-benzoyloxy-5,6α-dibromo-5β-cholestane 
• 71-43-2 benzene 
• 57-88-5 cholesterol 
• 98-88-4 benzoyl chloride 
• 57-88-5 cholesterol 
• 604-32-0 cholesteryl benzoate 

Downstream Products

• 58497-26-0 24-oxo-3β-cholesteryl benzoate 
• 604-32-0 cholesteryl benzoate 
• 69343-22-2 3β-Benzoyloxy-cholest-5-en-16-on 
• 2140-46-7 25-hydroxychlolesterol 
• 516-72-3 20(S)-hydroxycholesterol 
• 34048-78-7 3β-benzoyloxy-5,6α-dibromo-5β-cholestane 
• 17320-10-4 4β-hydroxycholesterol 

Relevant academic research and scientific papers

Preparation of oxysterols by c–h oxidation of dibromocholestane with ru(Bpga) catalyst

Seven mono-and dihydroxycholesterols were prepared by direct C–H oxidation of the cholestane skeleton with a recently developed Ru(Bpga) catalyst (Ru(Bpga) = [RuCl (bpga) (PPh3 )] Cl; bpga = 2-(bis(pyridin-2-ylmethyl)amino)-N-(2,6-dimethylphenyl)acetamide)). Due to the high selectivity of the Ru(Bpga) complex for tertiary C–H, the reaction afforded a mixture of 25-, 20-, 17-, and 14-oxygenated cholesterols that could be easily separated by high-performance liquid chromatography. These results suggest that late-stage C–H oxidation could be a viable strategy for preparing candidate metabolites of biologically important molecules.