1-cyclohexyl-2-p-tolylaziridine

Base Information

• Chemical Name: 1-cyclohexyl-2-p-tolylaziridine
• CAS No.: 1032817-96-1
• Molecular Formula: C₁₅H₂₁N
• Molecular Weight: 215.338
• Mol file: 1032817-96-1.mol

Synonyms:1-cyclohexyl-2-p-tolylaziridine

Chemical Property of 1-cyclohexyl-2-p-tolylaziridine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-cyclohexyl-2-p-tolylaziridine

There total 2 articles about 1-cyclohexyl-2-p-tolylaziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-ethenyl-4-methylbenzene (622-97-9,24936-41-2) + cyclohexylamine (108-91-8,157973-60-9) → 1-cyclohexyl-2-p-tolylaziridine (1032817-96-1)

Guidance literature:

1-ethenyl-4-methylbenzene; With dimethylbromosulphonium bromide; In acetonitrile; for 0.166667h; Cooling with ice;

cyclohexylamine; In water; at 20 ℃;

DOI:10.1039/c1gc15581d

Reference yield:

[2-bromo-1-(4-methylphenyl)ethyl]dimethylsulfonium bromide (1032818-10-2) + cyclohexylamine (108-91-8,157973-60-9) → 1-cyclohexyl-2-p-tolylaziridine (1032817-96-1)

Guidance literature:

In water;

DOI:10.1021/jo800269v

Reference yield: 99.0%

1-cyclohexyl-2-p-tolylaziridine (1032817-96-1) + carbon dioxide (124-38-9,18923-20-1) → 3-cyclohexyl-5-p-tolyloxazolidin-2-one (1032818-03-3)

Guidance literature:

With pyridine hydroiodide; at 60 ℃; for 48h; under 22502.3 Torr; regioselective reaction; Autoclave;

DOI:10.1039/c1gc15581d

upstream raw materials:

[2-bromo-1-(4-methylphenyl)ethyl]dimethylsulfonium bromide

cyclohexylamine

1-ethenyl-4-methylbenzene

Downstream raw materials:

3-cyclohexyl-5-p-tolyloxazolidin-2-one