Methyl 4-amino-3-methylisoxazole-5-carboxylate

Base Information

Chemical Name:Methyl 4-amino-3-methylisoxazole-5-carboxylate
CAS No.:83988-30-1
Molecular Formula:C₆H₈N₂O₃
Molecular Weight:156.141
Hs Code.:2934999090
European Community (EC) Number:868-669-9
Mol file:83988-30-1.mol

Synonyms:methyl 4-amino-3-methylisoxazole-5-carboxylate;83988-30-1;methyl 4-amino-3-methyl-1,2-oxazole-5-carboxylate;MFCD08689882;METHYL-4-AMINO-3-METHYL-ISOXAZOLE-5-CARBOXYLATE;SCHEMBL18952788;AKOS006290513;AS-54924;SY124619;CS-0036833;methyl4-amino-3-methylisoxazole-5-carboxylate;EN300-268679;W11092;5-Isoxazolecarboxylicacid,4-amino-3-methyl-,methylester(9CI)

Suppliers and Price of Methyl 4-amino-3-methylisoxazole-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl4-Amino-3-methyl-1,2-oxazole-5-carboxylate
50mg
$ 75.00

Sigma-Aldrich
Methyl 4-amino-3-methylisoxazole-5-carboxylate
1g
$ 1070.00

Matrix Scientific
Methyl 4-amino-3-methylisoxazole-5-carboxylate 95%
1g
$ 1203.00

Matrix Scientific
Methyl 4-amino-3-methylisoxazole-5-carboxylate 95%
250mg
$ 722.00

American Custom Chemicals Corporation
Methyl 4-amino-3-methylisoxazole-5-carboxylate 95.00%
5MG
$ 504.33

AK Scientific
methyl4-amino-3-methyl-1,2-oxazole-5-carboxylate
250mg
$ 317.60

Total 3 raw suppliers

Chemical Property of Methyl 4-amino-3-methylisoxazole-5-carboxylate

Chemical Property:

PSA：78.35000
LogP:0.93300
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:156.05349212
Heavy Atom Count:11
Complexity:162

Purity/Quality:: Methyl4-Amino-3-methyl-1,2-oxazole-5-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NOC(=C1N)C(=O)OC

Technology Process of Methyl 4-amino-3-methylisoxazole-5-carboxylate

There total 1 articles about Methyl 4-amino-3-methylisoxazole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 67-56-1
methanol

: 83988-31-2
4-amino-3-methylisoxazole-5-carboxylic acid

: 83988-30-1
methyl 4-amino-3-methylisoxazole-5-carboxylate

Guidance literature:: With hydrogenchloride; for 72h; Ambient temperature;
DOI:10.1039/P19820002391

Reference yield:

: 83988-30-1
methyl 4-amino-3-methylisoxazole-5-carboxylate

: 83988-34-5
5,7-dihydroxy-3-methylisoxazolo<4,5-b>pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / Et₃N / CH₂Cl₂ / 2 h / Heating

2: 90 percent / sodium ethoxide / ethanol / 1.5 h / Heating

3: 92 percent / aq. sodium hydroxide / 2 h / 100 °C

With sodium hydroxide; sodium ethanolate; triethylamine; In ethanol; dichloromethane;
DOI:10.1039/P19820002391

Reference yield:

: 83988-30-1
methyl 4-amino-3-methylisoxazole-5-carboxylate

: 83988-38-9
5-hydrazino-3-methylisoxazolo<4,5-b>pyridine

Guidance literature:: Multi-step reaction with 7 steps

1: 91 percent / Et₃N / CH₂Cl₂ / 2 h / Heating

2: 90 percent / sodium ethoxide / ethanol / 1.5 h / Heating

3: 92 percent / aq. sodium hydroxide / 2 h / 100 °C

4: 52 percent / phenylphosphonic dichloride / 1.5 h / 160 °C

5: 92 percent / hydrazine hydrate / dioxane / 1 h / 100 °C

6: 82 percent / aq. NaOH, air, 5-hydrazino-3-methylisoxazolo<4,5-b>pyridine

7: 70 percent / hydrazine / 2 h / 90 - 95 °C

With P,P-dichlorophenylphosphine oxide; sodium hydroxide; air; sodium ethanolate; hydrazine hydrate; triethylamine; 5-hydrazino-3-methylisoxazolo<4,5-b>pyridine; hydrazine; In 1,4-dioxane; ethanol; dichloromethane;
DOI:10.1039/P19820002391