5-bromo-2-(4-fluorophenyl)-1H-indole

Base Information

Chemical Name:5-bromo-2-(4-fluorophenyl)-1H-indole
CAS No.:76609-17-1
Molecular Formula:C₁₄H₉BrFN
Molecular Weight:290.135
Hs Code.:
DSSTox Substance ID:DTXSID201289899

Synonyms:5-bromo-2-(4-fluorophenyl)-1H-indole;76609-17-1;SCHEMBL6585488;DTXSID201289899

Suppliers and Price of 5-bromo-2-(4-fluorophenyl)-1H-indole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-bromo-2-(4-fluorophenyl)-1H-indole

Chemical Property:

XLogP3:4.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:288.99024
Heavy Atom Count:17
Complexity:265

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CC3=C(N2)C=CC(=C3)Br)F

Technology Process of 5-bromo-2-(4-fluorophenyl)-1H-indole

There total 5 articles about 5-bromo-2-(4-fluorophenyl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1196131-73-3
1-(4-bromophenyl)-2-(1-(4-fluorophenyl)ethylidene)hydrazine

: 76609-17-1
5-bromo-2-(4-fluorophenyl)-1H-indole

Guidance literature:: With PPA; at 120 ℃; for 4h;
DOI:10.1002/jhet.179

Reference yield: 79.0%

: 1765-93-1
4-fluoroboronic acid

: N-(4-bromo-2-(cyanomethyl)-phenyl)acetamide

: 76609-17-1
5-bromo-2-(4-fluorophenyl)-1H-indole

Guidance literature:: With potassium fluoride; 5,5'-dimethyl-2,2'-bipyridine; trifluorormethanesulfonic acid; palladium diacetate; In tetrahydrofuran; water; at 80 ℃; for 48h; chemoselective reaction; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.joc.7b00148

Reference yield: 64.0%

: 882855-95-0
2-(2-amino-5-bromophenyl)acetonitrile

: potassim 4-fluorophenyltrifluoroborate

: 76609-17-1
5-bromo-2-(4-fluorophenyl)-1H-indole

Guidance literature:: With 4,4'-dimethyl-2,2'-bipyridines; bis(acetylacetonato)palladium(II); toluene-4-sulfonic acid; In water; at 80 ℃; for 48h; Inert atmosphere; Schlenk technique;
DOI:10.1039/c7ob00572e