5,5-dimethoxy-1-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-1-en-3-one

Base Information

• Chemical Name: 5,5-dimethoxy-1-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-1-en-3-one
• CAS No.: 85458-25-9
• Molecular Formula: C₁₆H₂₆O₃
• Molecular Weight: 266.381
• Mol file: 85458-25-9.mol

Synonyms:5,5-dimethoxy-1-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-1-en-3-one

Chemical Property of 5,5-dimethoxy-1-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-1-en-3-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,5-dimethoxy-1-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-1-en-3-one

There total 4 articles about 5,5-dimethoxy-1-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-1-en-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Methyl formate (107-31-3) + Sodium; (E)-3-hydroxy-5-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-4-en-1-olate → 5,5-dimethoxy-1-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-1-en-3-one (85458-25-9)

Guidance literature:

With acetyl chloride; In methanol;

DOI:10.1016/S0040-4039(00)76832-8

Reference yield: 80.0%

methanol (67-56-1) + 1-hydroxy-5-(2,6,6-trimethyl-cyclohex-1-enyl)-penta-1,4-dien-3-one sel de sodium → 5,5-dimethoxy-1-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-1-en-3-one (85458-25-9)

Guidance literature:

With sulfuric acid;

DOI:10.1016/S0040-4039(99)01963-2

Reference yield:

(E)-β-ionone (79-77-6,14901-07-6) → 5,5-dimethoxy-1-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-1-en-3-one (85458-25-9)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOMe / pentane

2: H₂SO₄

With sulfuric acid; sodium methylate; In pentane;

DOI:10.1081/SCC-100106030

upstream raw materials:

Methyl formate

methanol

1-hydroxy-5-(2,6,6-trimethyl-cyclohex-1-enyl)-penta-1,4-dien-3-one

(E)-β-ionone

Downstream raw materials:

9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenal

11-cis-9-Demethylretinal

5-(2,6,6-trimethylcyclohex-1-enyl)penta-2,4-dien-1-ol

all-trans-9-desmethyltretinal