N-(p-toluenesulfonyl)-2-(2-bromo-4,5-methylenedioxyphenyl)aziridine

Base Information

• Chemical Name: N-(p-toluenesulfonyl)-2-(2-bromo-4,5-methylenedioxyphenyl)aziridine
• CAS No.: 1236009-81-6
• Molecular Formula: C₁₆H₁₄BrNO₄S
• Molecular Weight: 396.261
• Mol file: 1236009-81-6.mol

Synonyms:N-(p-toluenesulfonyl)-2-(2-bromo-4,5-methylenedioxyphenyl)aziridine

Chemical Property of N-(p-toluenesulfonyl)-2-(2-bromo-4,5-methylenedioxyphenyl)aziridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of N-(p-toluenesulfonyl)-2-(2-bromo-4,5-methylenedioxyphenyl)aziridine

There total 1 articles about N-(p-toluenesulfonyl)-2-(2-bromo-4,5-methylenedioxyphenyl)aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloroamine-T (127-65-1) + 1-bromo-2-ethenyl-4,5-(methylenedioxy)benzene (79809-06-6) → N-(p-toluenesulfonyl)-2-(2-bromo-4,5-methylenedioxyphenyl)aziridine (1236009-81-6)

Guidance literature:

With iodine; In acetonitrile; at 20 ℃; for 24h; Schlenk technique;

DOI:10.1021/acs.orglett.1c01077

Reference yield: 69.0%

N-(p-toluenesulfonyl)-2-(2-bromo-4,5-methylenedioxyphenyl)aziridine (1236009-81-6) + 1-cyclohexyl-2,4,6-triphenylpyridin-1-ium tetrafluoroborate salt → N-(2-(6-bromobenzo[d][1,3]dioxol-5-yl)-2-(1-cyclohexyl-2,4,6-triphenyl-1,4-dihydropyridin-4-yl)ethyl)-4-methylbenzenesulfonamide

Guidance literature:

With nickel(II) bromide dimethoxyethane; tris(2,2'-bipyridyl)ruthenium dichloride; 2,6-bis(pyrazole)pyridine; triethylamine; In N,N-dimethyl acetamide; acetonitrile; at 20 ℃; for 12h; Schlenk technique; Inert atmosphere; Irradiation;

DOI:10.1021/acs.orglett.1c01077

upstream raw materials:

chloroamine-T

1-bromo-2-ethenyl-4,5-(methylenedioxy)benzene