(2R,4R)-(-)-4-tert-butyldiphenylsilyloxymethyl-2-fluoro-γ-butyrolactone

Base Information

Chemical Name:(2R,4R)-(-)-4-tert-butyldiphenylsilyloxymethyl-2-fluoro-γ-butyrolactone
CAS No.:398133-29-4
Molecular Formula:C₂₁H₂₅FO₃Si
Molecular Weight:372.512
Hs Code.:

Synonyms:(2R,4R)-(-)-4-tert-butyldiphenylsilyloxymethyl-2-fluoro-γ-butyrolactone

Suppliers and Price of (2R,4R)-(-)-4-tert-butyldiphenylsilyloxymethyl-2-fluoro-γ-butyrolactone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,4R)-(-)-4-tert-butyldiphenylsilyloxymethyl-2-fluoro-γ-butyrolactone

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Technology Process of (2R,4R)-(-)-4-tert-butyldiphenylsilyloxymethyl-2-fluoro-γ-butyrolactone

There total 1 articles about (2R,4R)-(-)-4-tert-butyldiphenylsilyloxymethyl-2-fluoro-γ-butyrolactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 212954-52-4
(R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-fluoro-5H-furan-2-one

: 398133-29-4
(2R,4R)-(-)-4-tert-butyldiphenylsilyloxymethyl-2-fluoro-γ-butyrolactone

Guidance literature:: With hydrogen; palladium; In ethyl acetate;
DOI:10.1021/ol0171665

Reference yield: 83.0%

: 77-78-1
dimethyl sulfate

: 398133-29-4
(2R,4R)-(-)-4-tert-butyldiphenylsilyloxymethyl-2-fluoro-γ-butyrolactone

: 398133-30-7
(2R,4S)-5-(tert-Butyl-diphenyl-silanyloxy)-2-fluoro-4-iodo-pentanoic acid methyl ester

Guidance literature:: (2R,4R)-(-)-4-tert-butyldiphenylsilyloxymethyl-2-fluoro-γ-butyrolactone; With sodium hydroxide; In ethanol;

dimethyl sulfate; In dimethyl sulfoxide;

With 1H-imidazole; iodine; triphenylphosphine; In toluene; at 60 ℃; for 4h; Further stages.;
DOI:10.1021/ol0171665