3,4,6-tri-O-benzyl-1,2-O-methoxybenzylidene-α-D-glucopyranose

Base Information

• Chemical Name: 3,4,6-tri-O-benzyl-1,2-O-methoxybenzylidene-α-D-glucopyranose
• CAS No.: 40246-27-3
• Molecular Formula: C₄₁H₃₈O₈
• Molecular Weight: 658.748
• Mol file: 40246-27-3.mol

Synonyms:3,4,6-tri-O-benzyl-1,2-O-methoxybenzylidene-α-D-glucopyranose

Chemical Property of 3,4,6-tri-O-benzyl-1,2-O-methoxybenzylidene-α-D-glucopyranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4,6-tri-O-benzyl-1,2-O-methoxybenzylidene-α-D-glucopyranose

There total 2 articles about 3,4,6-tri-O-benzyl-1,2-O-methoxybenzylidene-α-D-glucopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzoyl chloride (98-88-4) + 1-O-benzoyl-3,4,6-tri-O-benzyl-D-glucopyranose → 3,4,6-tri-O-benzyl-1,2-O-methoxybenzylidene-α-D-glucopyranose (40246-27-3) + 1,2-di-O-benzoyl-3,4,6-tri-O-benzyl-β-D-glucopyranose (139332-51-7)

Guidance literature:

With pyridine; In dichloromethane; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1080/07328309808002906

Reference yield:

→ 3,4,6-tri-O-benzyl-1,2-O-methoxybenzylidene-α-D-glucopyranose (40246-27-3)

Guidance literature:

Reference yield: 86.0%

3,4,6-tri-O-benzyl-1,2-O-methoxybenzylidene-α-D-glucopyranose (40246-27-3) + Benzimidazol-2-thiol (134469-07-1) → benzimidazol-2-yl 2-O-benzoyl-3,4,6-tri-O-benzyl-1-thio-β-D-glucopyranoside (1309666-24-7)

Guidance literature:

3,4,6-tri-O-benzyl-1,2-O-methoxybenzylidene-α-D-glucopyranose; In acetonitrile; at 20 ℃; for 1h; Molecular sieve; Inert atmosphere;

Benzimidazol-2-thiol; With mercury dibromide; for 6h; Reflux;

DOI:10.1002/anie.201007212

upstream raw materials:

benzoyl chloride

Downstream raw materials:

methyl 2-O-(2-O-benzoyl-3,4,6-tri-O-benzyl-β-D-glucopyranosyl)-3,4,6-tri-O-benzyl-α-D-glucopyranoside

benzimidazol-2-yl 2-O-benzoyl-3,4,6-tri-O-benzyl-1-thio-β-D-glucopyranoside

2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-galactopyranosyl chloride

Benzoic acid (3R,4S,5S,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-(2,2,2-trifluoro-ethanesulfonyloxy)-tetrahydro-pyran-3-yl ester