4,5-bis-(p-methoxyphenyl)pentanoic acid

Base Information

• Chemical Name: 4,5-bis-(p-methoxyphenyl)pentanoic acid
• CAS No.: 79754-48-6
• Molecular Formula: C₁₉H₂₂O₄
• Molecular Weight: 314.381
• Mol file: 79754-48-6.mol

Synonyms:4,5-bis-(p-methoxyphenyl)pentanoic acid

Chemical Property of 4,5-bis-(p-methoxyphenyl)pentanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,5-bis-(p-methoxyphenyl)pentanoic acid

There total 25 articles about 4,5-bis-(p-methoxyphenyl)pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4,5-bis-(p-methoxyphenyl)pentanal (70738-51-1) → 4,5-bis-(p-methoxyphenyl)pentanoic acid (79754-48-6)

Guidance literature:

With sodium hydroxide; silver nitrate; In ethanol; water; for 4h; Ambient temperature;

Reference yield: 63.0%

4,5-bis-p-methoxyphenylpenta-2,4-dienoic acid (79754-55-5) → 4,5-bis-(p-methoxyphenyl)pentanoic acid (79754-48-6)

Guidance literature:

With sodium hydroxide; nickel-aluminium alloy; at 80 ℃; for 2h;

DOI:10.1039/P19810002662

Reference yield:

1,4-di(4-methoxyphenyl)ethanone (120-44-5) → 4,5-bis-(p-methoxyphenyl)pentanoic acid (79754-48-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) magnesium / 1.) tetahydrofuran, 35 deg c,1 h, 2.) room temperature

2: 87 percent / hydrogen, sulphuric acid / 5 percent palladium-carbon / methanol

3: 99 percent / sulphuric acid / dioxane; H₂O / Ambient temperature

4: 80 percent / silver nitrate, sodium hydroxide / ethanol; H₂O / 4 h / Ambient temperature

With sodium hydroxide; sulfuric acid; hydrogen; silver nitrate; magnesium; palladium on activated charcoal; In 1,4-dioxane; methanol; ethanol; water;

upstream raw materials:

4,5-bis-p-methoxyphenylpenta-2,4-dienoic acid

4,5-bis-p-methoxyphenyl-5-oxopentanoic acid

4,5-bis(4-methoxyphenyl)-5-oxopentanenitrile

4,5-bis-(p-methoxyphenyl)pentanal

Downstream raw materials:

7-hydroxy-4-p-hydroxybenzyl-1,2,3,4-tetrahydro-1-naphthol

7-hydroxy-4-p-hydroxybenzyl-3,4-dihydronaphthalen-1(2H)-one

(+/-)-sequirin D

7-methoxy-4-p-methoxybenzyl-1,2,3,4-tetrahydro-1-naphthol