1-(2-benzoyloxyethoxymethyl)-4-methoxy-5-methoxymethyl-6-methyluracil

Base Information

• Chemical Name: 1-(2-benzoyloxyethoxymethyl)-4-methoxy-5-methoxymethyl-6-methyluracil
• CAS No.: 155100-01-9
• Molecular Formula: C₁₇H₂₀N₂O₆
• Molecular Weight: 348.356
• Mol file: 155100-01-9.mol

Synonyms:1-(2-benzoyloxyethoxymethyl)-4-methoxy-5-methoxymethyl-6-methyluracil

Chemical Property of 1-(2-benzoyloxyethoxymethyl)-4-methoxy-5-methoxymethyl-6-methyluracil

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2-benzoyloxyethoxymethyl)-4-methoxy-5-methoxymethyl-6-methyluracil

There total 4 articles about 1-(2-benzoyloxyethoxymethyl)-4-methoxy-5-methoxymethyl-6-methyluracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1-(2-benzoyloxyethoxymethyl)-4-methoxy-5-methoxymethyl-6-methyl-2(1H)-pyrimidinone (155100-11-1) → 1-(2-benzoyloxyethoxymethyl)-4-methoxy-5-methoxymethyl-6-methyluracil (155100-01-9)

Guidance literature:

With hydrogenchloride; In chloroform; for 10h; Ambient temperature;

DOI:10.1135/cccc19932955

Reference yield:

(2-benzoyloxyethyl)oxymethyl chloride (58305-05-8) → 1-(2-benzoyloxyethoxymethyl)-4-methoxy-5-methoxymethyl-6-methyluracil (155100-01-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 52 percent / Na₂CO₃ / CH₂Cl₂ / 4 h / Ambient temperature

2: 78 percent / HCl / CHCl₃ / 10 h / Ambient temperature

With hydrogenchloride; sodium carbonate; In dichloromethane; chloroform;

DOI:10.1135/cccc19932955

Reference yield:

2,4-Dichloro-5-chloromethyl-6-methyl-pyrimidine (16768-43-7) → 1-(2-benzoyloxyethoxymethyl)-4-methoxy-5-methoxymethyl-6-methyluracil (155100-01-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 73 percent / methanol / 0.5 h / Heating

2: 52 percent / Na₂CO₃ / CH₂Cl₂ / 4 h / Ambient temperature

3: 78 percent / HCl / CHCl₃ / 10 h / Ambient temperature

With hydrogenchloride; sodium carbonate; In methanol; dichloromethane; chloroform;

DOI:10.1135/cccc19932955

upstream raw materials:

1-(2-benzoyloxyethoxymethyl)-4-methoxy-5-methoxymethyl-6-methyl-2(1H)-pyrimidinone

(2-benzoyloxyethyl)oxymethyl chloride

2,4-Dichloro-5-chloromethyl-6-methyl-pyrimidine

2,4-dimethoxy-5-methoxymethyl-6-methylpyrimidine