4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylbenzeneacetic acid, methyl ester hydrochloride

Base Information

• Chemical Name: 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylbenzeneacetic acid, methyl ester hydrochloride
• CAS No.: 343255-29-8
• Molecular Formula: C₃₃H₄₁NO₄*ClH
• Molecular Weight: 552.154
• Mol file: 343255-29-8.mol

Synonyms:4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylbenzeneacetic acid, methyl ester hydrochloride

Chemical Property of 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylbenzeneacetic acid, methyl ester hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylbenzeneacetic acid, methyl ester hydrochloride

There total 1 articles about 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylbenzeneacetic acid, methyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-oxobutyl]-α,α-dimethylbenzeneacetic acid, methyl ester hydrochloride (169280-33-5) → 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylbenzeneacetic acid, methyl ester hydrochloride (343255-29-8)

Guidance literature:

4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-oxobutyl]-α,α-dimethylbenzeneacetic acid, methyl ester hydrochloride; With sodium tetrahydroborate; In methanol; for 1h;

With sodium hydroxide; for 3h; Heating / reflux;

Reference yield: 94.0%

4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylbenzeneacetic acid, methyl ester hydrochloride (343255-29-8) → 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylbenzeneacetic Acid, Methyl Ester Hydrochloride

Guidance literature:

With hydrogenchloride; sodium hydroxide; sodium borohydrid; In methanol;

upstream raw materials:

4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-oxobutyl]-α,α-dimethylbenzeneacetic acid, methyl ester hydrochloride