[1(S)-(4-fluorobenzoyl)-2,2-dimethylpropyl]carbamic acid-tert-butyl ester

Base Information

Chemical Name:[1(S)-(4-fluorobenzoyl)-2,2-dimethylpropyl]carbamic acid-tert-butyl ester
CAS No.:301684-96-8
Molecular Formula:C₁₇H₂₄FNO₃
Molecular Weight:309.381
Hs Code.:

Synonyms:[1(S)-(4-fluorobenzoyl)-2,2-dimethylpropyl]carbamic acid-tert-butyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [1(S)-(4-fluorobenzoyl)-2,2-dimethylpropyl]carbamic acid-tert-butyl ester

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Technology Process of [1(S)-(4-fluorobenzoyl)-2,2-dimethylpropyl]carbamic acid-tert-butyl ester

There total 1 articles about [1(S)-(4-fluorobenzoyl)-2,2-dimethylpropyl]carbamic acid-tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 210711-68-5
[1(S)-(methoxy-methyl-carbamoyl)-2,2-dimethylpropyl]-carbamic acid-tert-butyl ester

: 352-13-6
4-flourophenylmagnesium bromide

: 301684-96-8
[1(S)-(4-fluorobenzoyl)-2,2-dimethylpropyl]carbamic acid-tert-butyl ester

Guidance literature:: In tetrahydrofuran; at 0 - 20 ℃; for 20.5h;

Reference yield: 88.0%

: 301684-96-8
[1(S)-(4-fluorobenzoyl)-2,2-dimethylpropyl]carbamic acid-tert-butyl ester

: 301684-97-9
2(S)-amino-1-(4-fluorophenyl)-3,3-dimethyl-butan-1-one

Guidance literature:: [1(S)-(4-fluorobenzoyl)-2,2-dimethylpropyl]carbamic acid-tert-butyl ester; With trifluoroacetic acid; In dichloromethane; at 0 - 5 ℃; for 16h;

With Dowex 1X₈-400; In methanol;