2-(2-Octylphenyl)ethyl Alcohol

Base Information

• Chemical Name: 2-(2-Octylphenyl)ethyl Alcohol
• CAS No.: 162358-94-3
• Molecular Formula: C₁₆H₂₆O
• Molecular Weight: 234.382
• Mol file: 162358-94-3.mol

Synonyms:2-(2-Octylphenyl)ethyl Alcohol

Chemical Property of 2-(2-Octylphenyl)ethyl Alcohol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-Octylphenyl)ethyl Alcohol

There total 9 articles about 2-(2-Octylphenyl)ethyl Alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-octylphenylacetate (162358-93-2) → 2-(2-Octylphenyl)ethyl Alcohol (162358-94-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1021/jm000173z

Reference yield:

1-Bromoheptane (629-04-9) → 2-(2-Octylphenyl)ethyl Alcohol (162358-94-3)

Guidance literature:

Multi-step reaction with 7 steps

1.1: Mg / tetrahydrofuran / 1 h / 40 °C

1.2: 49 percent / tetrahydrofuran / 1 h / 20 °C

2.1: 82 percent / P₂O₅ / benzene / 2 h / Heating

3.1: Mg / tetrahydrofuran / 0.5 h / 50 °C

3.2: 88 percent / tetrahydrofuran / 15 h / 20 °C

4.1: 82 percent / H₂ / 5percent Pd/C / ethanol / 4 h

5.1: Triton B / methanol; dioxane / 2 h / 80 °C

6.1: HCl / 0.5 h / 20 °C

7.1: LiAlH₄ / tetrahydrofuran / 1 h / 20 °C

With hydrogenchloride; lithium aluminium tetrahydride; hydrogen; phosphorus pentoxide; N-benzyl-trimethylammonium hydroxide; magnesium; 5percent Pd/C; In tetrahydrofuran; 1,4-dioxane; methanol; ethanol; benzene; 1.1: Metallation / 1.2: Grignard reaction / 2.1: Dehydration / 3.1: Metallation / 3.2: Formylation / 4.1: Catalytic hydrogenation / 5.1: Knoevenagel condensation / 6.1: ethanolysis / 7.1: Reduction;

DOI:10.1021/jm000173z

Reference yield:

ortho-bromobenzaldehyde (6630-33-7) → 2-(2-Octylphenyl)ethyl Alcohol (162358-94-3)

Guidance literature:

Multi-step reaction with 7 steps

1.1: Mg / tetrahydrofuran / 1 h / 40 °C

1.2: 49 percent / tetrahydrofuran / 1 h / 20 °C

2.1: 82 percent / P₂O₅ / benzene / 2 h / Heating

3.1: Mg / tetrahydrofuran / 0.5 h / 50 °C

3.2: 88 percent / tetrahydrofuran / 15 h / 20 °C

4.1: 82 percent / H₂ / 5percent Pd/C / ethanol / 4 h

5.1: Triton B / methanol; dioxane / 2 h / 80 °C

6.1: HCl / 0.5 h / 20 °C

7.1: LiAlH₄ / tetrahydrofuran / 1 h / 20 °C

With hydrogenchloride; lithium aluminium tetrahydride; hydrogen; phosphorus pentoxide; N-benzyl-trimethylammonium hydroxide; magnesium; 5percent Pd/C; In tetrahydrofuran; 1,4-dioxane; methanol; ethanol; benzene; 1.1: Metallation / 1.2: Grignard reaction / 2.1: Dehydration / 3.1: Metallation / 3.2: Formylation / 4.1: Catalytic hydrogenation / 5.1: Knoevenagel condensation / 6.1: ethanolysis / 7.1: Reduction;

DOI:10.1021/jm000173z

upstream raw materials:

ethyl 2-octylphenylacetate

1-Bromoheptane

ortho-bromobenzaldehyde

2-(n-Octyl)benzaldehyde

Downstream raw materials:

2-Acetamido-1,3-diacetoxy-2-[2-(2-octylphenyl)ethyl]propane

diethyl 2-Acetamido-2-[2-(2-octylphenyl)ethyl]malonate

2-octylphenethyl iodide

2-(2-Octylphenyl)ethyl Methanesulfonate