phenyl(2H-tetrazol-5-yl)methanamine

Base Information

Chemical Name:phenyl(2H-tetrazol-5-yl)methanamine
CAS No.:95898-94-5
Molecular Formula:C₈H₉N₅
Molecular Weight:175.193
Hs Code.:
DSSTox Substance ID:DTXSID701294207

Synonyms:phenyl(2H-tetrazol-5-yl)methanamine;95898-94-5;SCHEMBL9384051;DTXSID701294207;AKOS005264272;AKOS022529579;alpha-Phenyl-2H-tetrazole-5-methanamine;EN300-43285;F51707

Suppliers and Price of phenyl(2H-tetrazol-5-yl)methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of phenyl(2H-tetrazol-5-yl)methanamine

Chemical Property:

XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:175.08579531
Heavy Atom Count:13
Complexity:157

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C2=NNN=N2)N

Technology Process of phenyl(2H-tetrazol-5-yl)methanamine

There total 6 articles about phenyl(2H-tetrazol-5-yl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 437768-39-3
(+/-)-N-tert-butoxycarbonyl phenylglycine tetrazole

: 95898-94-5
C-phenyl-C-(2H-tetrazol-5-yl)-methylamine

Guidance literature:: With hydrogenchloride; at 20 ℃; for 16h;
DOI:10.1016/j.bmcl.2006.09.095

Reference yield:

: 2900-27-8,3601-66-9,14675-97-9,33125-05-2
2-(tert-butoxycarbonylamino)-2-phenylacetic acid

: 95898-94-5
C-phenyl-C-(2H-tetrazol-5-yl)-methylamine

Guidance literature:: Multi-step reaction with 4 steps

1.1: TEA / tetrahydrofuran / 0.5 h / -10 °C

1.2: 90 percent / NH₃ / tetrahydrofuran / cooling

2.1: 100 percent / (CF₃CO)2O; TEA / tetrahydrofuran / 14 h / 20 °C

3.1: 83 percent / NaN₃; Et₃N*HCl / toluene / 16 h / 95 °C

4.1: 85 percent / aq. HCl / 16 h / 20 °C

With hydrogenchloride; sodium azide; TEA; triethylamine hydrochloride; trifluoroacetic anhydride; In tetrahydrofuran; toluene;
DOI:10.1016/j.bmcl.2006.09.095

Reference yield:

: 2835-06-5
phenylglycin

: 95898-94-5
C-phenyl-C-(2H-tetrazol-5-yl)-methylamine

Guidance literature:: Multi-step reaction with 5 steps

1.1: 67 percent / aq. NaOH / dioxane / 12 h / 20 °C

2.1: TEA / tetrahydrofuran / 0.5 h / -10 °C

2.2: 90 percent / NH₃ / tetrahydrofuran / cooling

3.1: 100 percent / (CF₃CO)2O; TEA / tetrahydrofuran / 14 h / 20 °C

4.1: 83 percent / NaN₃; Et₃N*HCl / toluene / 16 h / 95 °C

5.1: 85 percent / aq. HCl / 16 h / 20 °C

With hydrogenchloride; sodium hydroxide; sodium azide; TEA; triethylamine hydrochloride; trifluoroacetic anhydride; In tetrahydrofuran; 1,4-dioxane; toluene;
DOI:10.1016/j.bmcl.2006.09.095