C₁₇H₁₇N₅O₄

Base Information

• Chemical Name: C₁₇H₁₇N₅O₄
• CAS No.: 1365759-72-3
• Molecular Formula: C₁₇H₁₇N₅O₄
• Molecular Weight: 355.353
• Mol file: 1365759-72-3.mol

Synonyms:C₁₇H₁₇N₅O₄

Chemical Property of C₁₇H₁₇N₅O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₇N₅O₄

There total 6 articles about C₁₇H₁₇N₅O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

C17H19N3O4 (1365759-68-7) → C17H17N5O4 (1365759-72-3)

Guidance literature:

With tert.-butylnitrite; trimethylsilylazide; Combinatorial reaction / High throughput screening (HTS);

DOI:10.1021/co200200u

Reference yield:

tert-butyl 2,4-dioxopiperidine-1-carboxylate (845267-78-9) → C17H17N5O4 (1365759-72-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydride / tetrahydrofuran / Combinatorial reaction / High throughput screening (HTS)

1.2: Combinatorial reaction / High throughput screening (HTS)

2.1: acetic acid; zinc / dichloromethane / 0.08 h / 0 °C

3.1: tert.-butylnitrite; trimethylsilylazide / Combinatorial reaction / High throughput screening (HTS)

With tert.-butylnitrite; trimethylsilylazide; sodium hydride; acetic acid; zinc; In tetrahydrofuran; dichloromethane;

DOI:10.1021/co200200u

Reference yield:

t-butyl 3-(3-nitrophenyl)-4-oxo-6,7-dihydroisoxazolo[4,5-c]pyridine-5(4H)-carboxylate (1246303-75-2) → C17H17N5O4 (1365759-72-3)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid; zinc / dichloromethane / 0.08 h / 0 °C

2: tert.-butylnitrite; trimethylsilylazide / Combinatorial reaction / High throughput screening (HTS)

With tert.-butylnitrite; trimethylsilylazide; acetic acid; zinc; In dichloromethane;

DOI:10.1021/co200200u

upstream raw materials:

tert-butyl 2,4-dioxopiperidine-1-carboxylate

t-butyl 3-(3-nitrophenyl)-4-oxo-6,7-dihydroisoxazolo[4,5-c]pyridine-5(4H)-carboxylate

C₁₇H₁₉N₃O₄

3-(tert-butyloxycarbonylamino)propionic acid

Downstream raw materials:

C₂₁H₂₂N₆O₅

C₂₂H₂₄N₆O₅

C₂₃H₂₇N₇O₄

C₂₄H₂₅N₇O₄