Technology Process of (4S)-4-(4'-p-hydroxy)benzyl-4,5-dihydrooxazoline
There total 5 articles about (4S)-4-(4'-p-hydroxy)benzyl-4,5-dihydrooxazoline which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen; palladium(II) hydroxide;
In
tetrahydrofuran; methanol;
at 20 ℃;
for 6h;
DOI:10.1139/V10-162
- Guidance literature:
-
Multi-step reaction with 2 steps
1: toluene-4-sulfonic acid / toluene / 48 h / Inert atmosphere; Reflux
2: hydrogen; palladium(II) hydroxide / tetrahydrofuran; methanol / 6 h / 20 °C
With
hydrogen; palladium(II) hydroxide; toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol; toluene;
DOI:10.1139/V10-162
- Guidance literature:
-
Multi-step reaction with 3 steps
1: acetyl chloride / methanol; ethyl acetate / 24.5 h / 0 - 20 °C
2: toluene-4-sulfonic acid / toluene / 48 h / Inert atmosphere; Reflux
3: hydrogen; palladium(II) hydroxide / tetrahydrofuran; methanol / 6 h / 20 °C
With
hydrogen; palladium(II) hydroxide; toluene-4-sulfonic acid; acetyl chloride;
In
tetrahydrofuran; methanol; ethyl acetate; toluene;
DOI:10.1139/V10-162
