3-(azidomethyl)-N-cyclohexylbenzamidine

Base Information

• Chemical Name: 3-(azidomethyl)-N-cyclohexylbenzamidine
• CAS No.: 1634649-05-0
• Molecular Formula: C₁₄H₁₉N₅
• Molecular Weight: 257.338
• Mol file: 1634649-05-0.mol

Synonyms:3-(azidomethyl)-N-cyclohexylbenzamidine

Chemical Property of 3-(azidomethyl)-N-cyclohexylbenzamidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(azidomethyl)-N-cyclohexylbenzamidine

There total 3 articles about 3-(azidomethyl)-N-cyclohexylbenzamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H12N4O + cyclohexylamine (108-91-8,157973-60-9) → 3-(azidomethyl)-N-cyclohexylbenzamidine (1634649-05-0)

Guidance literature:

In methanol; at 30 ℃;

DOI:10.3390/molecules19055674

Reference yield:

3-(azidomethyl)benzonitrile (328552-90-5) → 3-(azidomethyl)-N-cyclohexylbenzamidine (1634649-05-0)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / 168 h / 20 °C / Cooling with ice

2: methanol / 30 °C

With hydrogenchloride; In methanol; 1: |Pinner Amidine Synthesis;

DOI:10.3390/molecules19055674

Reference yield:

m-(bromomethyl)benzonitrile (28188-41-2) → 3-(azidomethyl)-N-cyclohexylbenzamidine (1634649-05-0)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium azide / N,N-dimethyl-formamide; water / 1.5 h / 10 - 30 °C

2: hydrogenchloride / 168 h / 20 °C / Cooling with ice

3: methanol / 30 °C

With hydrogenchloride; sodium azide; In methanol; water; N,N-dimethyl-formamide; 2: |Pinner Amidine Synthesis;

DOI:10.3390/molecules19055674

upstream raw materials:

m-(bromomethyl)benzonitrile

3-(azidomethyl)benzonitrile

cyclohexylamine

Downstream raw materials:

3-((4-((4-nitrophenoxy)methyl)-1H-1,2,3-triazol-1-yl)methyl)-N-cyclohexylbenzamidine

N-cyclohexyl-3-((4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl)methyl)benzamidine