(R)-2-methyl-1-{3-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenoxyl]propyl}pyrrolidine

Base Information

Chemical Name:(R)-2-methyl-1-{3-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenoxyl]propyl}pyrrolidine
CAS No.:1005403-35-9
Molecular Formula:C₂₀H₃₂BNO₃
Molecular Weight:345.29
Hs Code.:

Synonyms:(R)-2-methyl-1-{3-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenoxyl]propyl}pyrrolidine

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Chemical Property of (R)-2-methyl-1-{3-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenoxyl]propyl}pyrrolidine

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Technology Process of (R)-2-methyl-1-{3-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenoxyl]propyl}pyrrolidine

There total 4 articles about (R)-2-methyl-1-{3-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenoxyl]propyl}pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 957061-13-1
2-[4-(3-bromopropoxy)phenyl]-4,4,5,5-tetramethyl-[1,3,2]-dioxaborolane

: 41720-98-3,54677-53-1,135324-85-5,174500-74-4
(R)-2-methylpyrrolidine hydrochloride

: 1005403-35-9
(R)-2-methyl-1-{3-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenoxyl]propyl}pyrrolidine

Guidance literature:: With potassium carbonate; In acetonitrile; at 78 ℃; for 36h;

Reference yield:

: 269409-70-3
4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

: 1005403-35-9
(R)-2-methyl-1-{3-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenoxyl]propyl}pyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 24 h / Reflux

2: potassium carbonate; sodium iodide / acetonitrile / 60 h / Reflux

With potassium carbonate; sodium iodide; In acetonitrile;
DOI:10.1021/jm200401v