4-(2-Oxo-2-phenyl-1-chloroethylidene)-2,2,5,5-tetramethylimidazolidine-1-oxyl

Base Information

• Chemical Name: 4-(2-Oxo-2-phenyl-1-chloroethylidene)-2,2,5,5-tetramethylimidazolidine-1-oxyl
• CAS No.: 84359-72-8
• Molecular Formula: C₁₅H₁₈ClN₂O₂
• Molecular Weight: 293.773
• Mol file: 84359-72-8.mol

Synonyms:4-(2-Oxo-2-phenyl-1-chloroethylidene)-2,2,5,5-tetramethylimidazolidine-1-oxyl

Chemical Property of 4-(2-Oxo-2-phenyl-1-chloroethylidene)-2,2,5,5-tetramethylimidazolidine-1-oxyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(2-Oxo-2-phenyl-1-chloroethylidene)-2,2,5,5-tetramethylimidazolidine-1-oxyl

There total 5 articles about 4-(2-Oxo-2-phenyl-1-chloroethylidene)-2,2,5,5-tetramethylimidazolidine-1-oxyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

C15H17Cl2N2O2 → 4-(2-Oxo-2-phenyl-1-chloroethylidene)-2,2,5,5-tetramethylimidazolidine-1-oxyl (84359-72-8)

Guidance literature:

C₁₅H₁₇Cl₂N₂O₂; With methyl magnesium iodide; In diethyl ether;

With manganese(IV) oxide; In chloroform; at 20 ℃; for 0.5h;

DOI:10.1002/ejoc.200200722

Reference yield:

4-phenylacetylidene-2,2,5,5-tetramethyl-3-imidazoline 1-oxide (84271-26-1) → 4-(2-Oxo-2-phenyl-1-chloroethylidene)-2,2,5,5-tetramethylimidazolidine-1-oxyl (84359-72-8)

Guidance literature:

With N-chloro-succinimide;

DOI:10.1007/BF02499074

Reference yield:

benzoic acid ethyl ester (93-89-0,99341-95-4) → 4-(2-Oxo-2-phenyl-1-chloroethylidene)-2,2,5,5-tetramethylimidazolidine-1-oxyl (84359-72-8)

Guidance literature:

Multi-step reaction with 3 steps

1: LDA

2: MnO₂

3: NCS

With manganese(IV) oxide; N-chloro-succinimide; lithium diisopropyl amide; 1: Acylation / 2: Oxidation / 3: Chlorination;

DOI:10.1007/BF02499074

upstream raw materials:

4-phenylacetylidene-2,2,5,5-tetramethyl-3-imidazoline 1-oxide

benzoic acid ethyl ester

1-hydroxy-4-phenylacylidine-2,2,5,5-tetramethylimidazolidine

1-hydroxy-2,2,4,5,5-pentamethyl-3-imidazoline

Downstream raw materials:

1-Hydroxy-4-(2-oxo-2-phenyl-1-chloroethylidene)-2,2,5,5-tetramethylimidazolidine

4-(1-imino-2-oxo-2-phenylethyl)-2,2,5,5-tetramethyl-3-imidazoline-1-oxyl

5,5-Dimethyl-4-oxo-2-phenyl-3-chloro-2-pyrroline

5,5-Dimethyl-3,4-dioxo-2-phenyl-1-pyrroline-1-oxide