3-(benzyloxy)-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-5-hydroxy-7-methoxy-4H-chromen-4-one

Base Information

• Chemical Name: 3-(benzyloxy)-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-5-hydroxy-7-methoxy-4H-chromen-4-one
• CAS No.: 498548-19-9
• Molecular Formula: C₃₆H₂₆O₇
• Molecular Weight: 570.598
• Mol file: 498548-19-9.mol

Synonyms:3-(benzyloxy)-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-5-hydroxy-7-methoxy-4H-chromen-4-one

Chemical Property of 3-(benzyloxy)-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-5-hydroxy-7-methoxy-4H-chromen-4-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(benzyloxy)-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-5-hydroxy-7-methoxy-4H-chromen-4-one

There total 10 articles about 3-(benzyloxy)-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-5-hydroxy-7-methoxy-4H-chromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

3-(benzyloxy)-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-5,7-dihydroxy-4H-chromen-4-one (498548-17-7) + methyl iodide (74-88-4) → 3-(benzyloxy)-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-5-hydroxy-7-methoxy-4H-chromen-4-one (498548-19-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 25 ℃; for 12h; regioselective reaction; Inert atmosphere;

DOI:10.1016/j.ejmech.2012.04.044

Reference yield: 15.0%

dimethyl sulfate (77-78-1) + 3-(benzyloxy)-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-5,7-dihydroxy-4H-chromen-4-one (498548-17-7) → 3-(benzyloxy)-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-5,7-dimethoxy-4H-chromen-4-one (1393953-78-0) + 3-(benzyloxy)-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-5-hydroxy-7-methoxy-4H-chromen-4-one (498548-19-9)

Guidance literature:

With potassium carbonate; In acetone; at 60 ℃; for 3h;

Reference yield:

2-(2,2-diphenylbenzo[1,3]dioxol-5-yl)-3,5,7-trihydroxychromen-4-one (357194-03-7) → 3-(benzyloxy)-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-5-hydroxy-7-methoxy-4H-chromen-4-one (498548-19-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 64 percent / K₂CO₃ / dimethylformamide / 14 h / 0 - 20 °C

2: 60 percent / K₂CO₃ / dimethylformamide / 6 h

With potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(02)01306-6

upstream raw materials:

3-(benzyloxy)-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-5,7-dihydroxy-4H-chromen-4-one

methyl iodide

Dichlorodiphenylmethane

quercetol

Downstream raw materials:

3,5-Dihydroxy-7-methoxy-3',4'-diphenylmethylendioxy-flavon

rhamnetin

ombuin

rhamnazin