2'-O-(tert-butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine

Base Information

Chemical Name:2'-O-(tert-butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine
CAS No.:401812-99-5
Molecular Formula:C₂₄H₄₃N₅O₅Si₂
Molecular Weight:537.807
Hs Code.:
Mol file:401812-99-5.mol

Synonyms:2'-O-(tert-butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine

Suppliers and Price of 2'-O-(tert-butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2'-O-(tert-Butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine >95%
1g
$ 1103.00

Matrix Scientific
2'-O-(tert-Butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine >95%
500mg
$ 808.00

Crysdot
2-Amino-9-((4aR,6R,7R,7aR)-2,2-di-tert-butyl-7-((tert-butyldimethylsilyl)oxy)tetrahydro-4H-furo[3,2-d][1,3,2]dioxasilin-6-yl)-1H-purin-6(9H)-one 97%
1g
$ 764.00

Chemenu
2-Amino-9-((4aR,6R,7R,7aR)-2,2-di-tert-butyl-7-((tert-butyldimethylsilyl)oxy)tetrahydro-4H-furo[3,2-d][1,3,2]dioxasilin-6-yl)-1H-purin-6(9H)-one 97%
1g
$ 722.00

Total 6 raw suppliers

Chemical Property of 2'-O-(tert-butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

2'-O-(tert-Butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2'-O-(tert-butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine

There total 5 articles about 2'-O-(tert-butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.4%

: 126628-29-3
2-amino-9-((4aR,6R,7R,7aS)-2,2-di-tert-butyl-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxasilin-6-yl)-1,9-dihydro-6H-purin-6-one

: 18162-48-6
tert-butyldimethylsilyl chloride

: 401812-99-5
2'-O-(tert-butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine

Guidance literature:: 2-amino-9-((4aR,6R,7R,7aS)-2,2-di-tert-butyl-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxasilin-6-yl)-1,9-dihydro-6H-purin-6-one; With 1H-imidazole; In N,N-dimethyl-formamide; at 0 - 25 ℃; for 1h;

tert-butyldimethylsilyl chloride; at 60 ℃; for 2h;
DOI:10.1016/S0040-4039(02)00181-8

Reference yield: 75.0%

: 85272-31-7
di-tert-butylsilyl bis(trifluoromethanesulfonate)

: 18162-48-6
tert-butyldimethylsilyl chloride

: 118-00-3
G

: 401812-99-5
2'-O-(tert-butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine

Guidance literature:: di-tert-butylsilyl bis(trifluoromethanesulfonate); G; In N,N-dimethyl-formamide; at 0 ℃; for 0.25h; Inert atmosphere;

With 1H-imidazole; In N,N-dimethyl-formamide; at 0 ℃; for 0.0833333h; Inert atmosphere;

tert-butyldimethylsilyl chloride; In N,N-dimethyl-formamide; for 2h; Inert atmosphere; Heating;
DOI:10.1002/anie.201700537

Reference yield: 68.0%

: di-tert-butylsilyl bis(trifluoromethane sulfonate)

: 18162-48-6
tert-butyldimethylsilyl chloride

: 118-00-3
G

: 401812-99-5
2'-O-(tert-butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine

Guidance literature:: di-tert-butylsilyl bis(trifluoromethane sulfonate); G; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h; Inert atmosphere;

With 1H-imidazole; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.5h; Inert atmosphere;

tert-butyldimethylsilyl chloride; In N,N-dimethyl-formamide; at 60 ℃; for 2h; Inert atmosphere;
DOI:10.1002/anie.201916272